The experimental power of FR900359 to study Gq-regulated biological processes R Schrage, AL Schmitz, E Gaffal, S Annala, S Kehraus, D Wenzel, ... Nature communications 6 (1), 10156, 2015 | 363 | 2015 |
Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET Y Namkung, C Le Gouill, V Lukashova, H Kobayashi, M Hogue, E Khoury, ... Nature communications 7 (1), 12178, 2016 | 297 | 2016 |
Functional Roles of Cav1.3 (α1D) Calcium Channel in Sinoatrial Nodes: Insight Gained Using Gene-Targeted Null Mutant Mice Z Zhang, Y Xu, H Song, J Rodriguez, D Tuteja, Y Namkung, HS Shin, ... Circulation research 90 (9), 981-987, 2002 | 271 | 2002 |
Requirement for the L-type Ca2+ channel α1D subunit in postnatal pancreatic β cell generation Y Namkung, N Skrypnyk, MJ Jeong, T Lee, MS Lee, HL Kim, H Chin, ... The Journal of clinical investigation 108 (7), 1015-1022, 2001 | 199 | 2001 |
Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor Y Namkung, DR Sibley Journal of Biological Chemistry 279 (47), 49533-49541, 2004 | 191 | 2004 |
Null Mutation of α1D Ca2+ Channel Gene Results in Deafness but No Vestibular Defect in Mice H Dou, AE Vazquez, Y Namkung, H Chu, EL Cardell, L Nie, S Parson, ... Journal of the Association for Research in Otolaryngology 5, 215-226, 2004 | 158 | 2004 |
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ... Nature communications 8 (1), 15054, 2017 | 153 | 2017 |
Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors Y Namkung, C LeGouill, S Kumar, Y Cao, LB Teixeira, V Lukasheva, ... Science signaling 11 (559), eaat1631, 2018 | 133 | 2018 |
Targeted disruption of the Ca2+ channel β3 subunit reduces N-and L-type Ca2+ channel activity and alters the voltagedependent activation of P/Q-type Ca2+ channels in neurons Y Namkung, SM Smith, SB Lee, NV Skrypnyk, HL Kim, H Chin, ... Proceedings of the National Academy of Sciences 95 (20), 12010-12015, 1998 | 118 | 1998 |
G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor Y Namkung, C Dipace, JA Javitch, DR Sibley Journal of biological chemistry 284 (22), 15038-15051, 2009 | 107 | 2009 |
D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin RB Free, LA Hazelwood, DM Cabrera, HN Spalding, Y Namkung, ... Journal of Biological Chemistry 282 (29), 21285-21300, 2007 | 107 | 2007 |
G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation Y Namkung, C Dipace, E Urizar, JA Javitch, DR Sibley Journal of Biological Chemistry 284 (49), 34103-34115, 2009 | 82 | 2009 |
FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs SC Wright, MCA Canizal, T Benkel, K Simon, C Le Gouill, P Matricon, ... Science signaling 11 (559), eaar5536, 2018 | 60 | 2018 |
Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK E Khoury, L Nikolajev, M Simaan, Y Namkung, SA Laporte Journal of Biological Chemistry 289 (34), 23302-23317, 2014 | 52 | 2014 |
Quantifying biased signaling in GPCRs using BRET-based biosensors Y Namkung, O Radresa, S Armando, D Devost, A Beautrait, C Le Gouill, ... Methods 92, 5-10, 2016 | 46 | 2016 |
Pharmacological characterization of 2‐methoxy‐N‐propylnorapomorphine's interactions with D2 and D3 dopamine receptors M Skinbjerg, Y Namkung, C Halldin, RB Innis, DR Sibley Synapse 63 (6), 462-475, 2009 | 43 | 2009 |
Development of the visual pathway is disrupted in mice with a targeted disruption of the calcium channel β3‐subunit gene RJ Cork, Y Namkung, HS Shin, RR Mize Journal of Comparative Neurology 440 (2), 177-191, 2001 | 37 | 2001 |
D2 dopamine receptor expression and trafficking is regulated through direct interactions with ZIP OJ Kim, MA Ariano, Y Namkung, P Marinec, E Kim, J Han, DR Sibley Journal of neurochemistry 106 (1), 83-95, 2008 | 32 | 2008 |
Dynamic spatiotemporal determinants modulate GPCR: G protein coupling selectivity and promiscuity M Sandhu, A Cho, N Ma, E Mukhaleva, Y Namkung, S Lee, S Ghosh, ... Nature Communications 13 (1), 7428, 2022 | 31 | 2022 |
Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR V Lukasheva, D Devost, C Le Gouill, Y Namkung, RD Martin, JM Longpré, ... Scientific reports 10 (1), 8779, 2020 | 31 | 2020 |