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Siyu Chen
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Structure of the human Mediator-bound transcription preinitiation complex
R Abdella, A Talyzina, S Chen, CJ Inouye, R Tjian, Y He
Science 372 (6537), 52-56, 2021
1352021
Structural basis of long-range to short-range synaptic transition in NHEJ
S Chen, L Lee, T Naila, S Fishbain, A Wang, AE Tomkinson, ...
Nature 593 (7858), 294-298, 2021
1162021
Structural insights into the role of DNA-PK as a master regulator in NHEJ
S Chen, JP Lees-Miller, Y He, SP Lees-Miller
Genome Instability & Disease 2 (4), 195-210, 2021
312021
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ
S Chen, A Vogt, L Lee, T Naila, R McKeown, AE Tomkinson, ...
Science Advances 9 (22), eadg2838, 2023
172023
MbnH is a diheme MauG-like protein associated with microbial copper homeostasis
GE Kenney, LMK Dassama, AC Manesis, MO Ross, S Chen, BM Hoffman, ...
Journal of Biological Chemistry 294 (44), 16141-16151, 2019
82019
Tomogram reconstruction and sub-tomogram averaging to obtain full-length, auto-inhibited LRRK2 filaments on microtubules
S Chen, J Hutchings, D Singh
2024
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
S Chen, T Basiashvili, J Hutchings, MS Murillo, AV Suarez, JA Louro, ...
bioRxiv, 2024.06. 18.599606, 2024
2024
Quick guide to use paceTOMO for cryo-ET data collection from Titan Krios
J Hutchings, S Chen
2023
LRRK2 and LAMP1 immunofluorescence staining in various cell lines
S Chen
2023
Molecular architecture of LRRK2 in association with cellular organelles
T Basiashvili, S Kim, S Chen, J Hutchings, SL Reck-Peterson, E Villa
Biophysical Journal 122 (3), 544a, 2023
2023
Cryo-EM visualization of state transition during non-homologous end-joining (NHEJ)
S Chen, L Lee, T Naila, R McKeown, S Fishbain, A Vogt, A Wang, ...
Biophysical Journal 122 (3), 150a, 2023
2023
Structural Visualization of State Transition during Non-homologous End-Joining (NHEJ)
S Chen
Northwestern University, 2022
2022
Structural Basis of DNA Double-Strand Break Repair by NHEJ
S Chen, A Vogt, L Lee, T Naila, R McKeown, AE Tomkinson, ...
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