A red meat-derived glycan promotes inflammation and cancer progression AN Samraj, OMT Pearce, H Läubli, AN Crittenden, AK Bergfeld, K Banda, ... Proceedings of the National Academy of Sciences 112 (2), 542-547, 2015 | 444 | 2015 |
Sialic acids in cancer biology and immunity OMT Pearce, H Läubli Glycobiology 26 (2), 111-128, 2016 | 433 | 2016 |
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers OMT Pearce, RM Delaine-Smith, E Maniati, S Nichols, J Wang, S Böhm, ... Cancer discovery 8 (3), 304-319, 2018 | 283 | 2018 |
Interleukin-6 stimulates defective angiogenesis G Gopinathan, C Milagre, OMT Pearce, LE Reynolds, K Hodivala-Dilke, ... Cancer research 75 (15), 3098-3107, 2015 | 243 | 2015 |
Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer H Läubli, OMT Pearce, F Schwarz, SS Siddiqui, L Deng, MA Stanczak, ... Proceedings of the National Academy of Sciences 111 (39), 14211-14216, 2014 | 222 | 2014 |
Characterization of the extracellular matrix of normal and diseased tissues using proteomics A Naba, OMT Pearce, A Del Rosario, D Ma, H Ding, V Rajeeve, ... Journal of proteome research 16 (8), 3083-3091, 2017 | 214 | 2017 |
A strong B-cell response is part of the immune landscape in human high-grade serous ovarian metastases A Montfort, O Pearce, E Maniati, BG Vincent, L Bixby, S Böhm, T Dowe, ... Clinical Cancer Research 23 (1), 250-262, 2017 | 183 | 2017 |
Versican—a critical extracellular matrix regulator of immunity and inflammation TN Wight, I Kang, SP Evanko, IA Harten, MY Chang, OMT Pearce, ... Frontiers in immunology 11, 512, 2020 | 175 | 2020 |
Neoadjuvant chemotherapy modulates the immune microenvironment in metastases of tubo-ovarian high-grade serous carcinoma S Böhm, A Montfort, OMT Pearce, J Topping, P Chakravarty, GLA Everitt, ... Clinical Cancer Research 22 (12), 3025-3036, 2016 | 135 | 2016 |
Basement membrane stiffness determines metastases formation R Reuten, S Zendehroud, M Nicolau, L Fleischhauer, A Laitala, ... Nature materials 20 (6), 892-903, 2021 | 114 | 2021 |
Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid AK Bergfeld, OMT Pearce, SL Diaz, T Pham, A Varki Journal of Biological Chemistry 287 (34), 28865-28881, 2012 | 101 | 2012 |
Rapid trimming of cell surface polysialic acid (PolySia) by exovesicular sialidase triggers release of preexisting surface neurotrophin M Sumida, M Hane, U Yabe, Y Shimoda, OMT Pearce, M Kiso, T Miyagi, ... Journal of Biological Chemistry 290 (21), 13202-13214, 2015 | 99 | 2015 |
Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies OMT Pearce, H Läubli, A Verhagen, P Secrest, J Zhang, NM Varki, ... Proceedings of the National Academy of Sciences 111 (16), 5998-6003, 2014 | 78 | 2014 |
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade MA Stanczak, N Rodrigues Mantuano, N Kirchhammer, DE Sanin, ... Science translational medicine 14 (669), eabj1270, 2022 | 77 | 2022 |
TGFBI production by macrophages contributes to an immunosuppressive microenvironment in ovarian cancer LSM Lecker, C Berlato, E Maniati, R Delaine-Smith, OMT Pearce, O Heath, ... Cancer research 81 (22), 5706-5719, 2021 | 77 | 2021 |
Mouse ovarian cancer models recapitulate the human tumor microenvironment and patient response to treatment E Maniati, C Berlato, G Gopinathan, O Heath, P Kotantaki, A Lakhani, ... Cell reports 30 (2), 525-540. e7, 2020 | 71 | 2020 |
Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2–8-linked N-glycolylneuraminic acid to enzymatic cleavage LRL Davies, OMT Pearce, MB Tessier, S Assar, V Smutova, M Pajunen, ... Journal of Biological Chemistry 287 (34), 28917-28931, 2012 | 71 | 2012 |
FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer S Zaghdoudi, E Decaup, I Belhabib, R Samain, S Cassant‐Sourdy, ... EMBO molecular medicine 12 (11), e12010, 2020 | 69 | 2020 |
Cancer glycan epitopes: biosynthesis, structure and function OMT Pearce Glycobiology 28 (9), 670-696, 2018 | 69 | 2018 |
Siglec receptors impact mammalian lifespan by modulating oxidative stress F Schwarz, OMT Pearce, X Wang, AN Samraj, H Läubli, JO Garcia, H Lin, ... Elife 4, e06184, 2015 | 68 | 2015 |