TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS Y Wang, L Su, MD Morin, BT Jones, LR Whitby, MMRP Surakattula, ... Proceedings of the National Academy of Sciences 113 (7), E884-E893, 2016 | 163 | 2016 |
MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses M Zeng, Z Hu, X Shi, X Li, X Zhan, XD Li, J Wang, JH Choi, K Wang, ... Science 346 (6216), 1486-1492, 2014 | 128 | 2014 |
Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice Y Wang, L Su, MD Morin, BT Jones, Y Mifune, H Shi, K Wang, X Zhan, ... Proceedings of the National Academy of Sciences 115 (37), E8698-E8706, 2018 | 94 | 2018 |
Real-time resolution of point mutations that cause phenovariance in mice T Wang, X Zhan, CH Bu, S Lyon, D Pratt, S Hildebrand, JH Choi, Z Zhang, ... Proceedings of the National Academy of Sciences 112 (5), E440-E449, 2015 | 88 | 2015 |
Creatine maintains intestinal homeostasis and protects against colitis E Turer, W McAlpine, K Wang, T Lu, X Li, M Tang, X Zhan, T Wang, ... Proceedings of the National Academy of Sciences 114 (7), E1273-E1281, 2017 | 62 | 2017 |
IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice JH Choi, K Wang, D Zhang, X Zhan, T Wang, CH Bu, CL Behrendt, ... Proceedings of the National Academy of Sciences 114 (7), E1196-E1204, 2017 | 61 | 2017 |
SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell–mediated immunity T Yue, X Zhan, D Zhang, R Jain, K Wang, JH Choi, T Misawa, L Su, ... Science 372 (6543), eaba4220, 2021 | 58 | 2021 |
Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function W McAlpine, L Sun, K Wang, A Liu, R Jain, M San Miguel, J Wang, ... Proceedings of the National Academy of Sciences 115 (49), E11523-E11531, 2018 | 52 | 2018 |
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling JH Choi, X Zhong, W McAlpine, TC Liao, D Zhang, B Fang, J Russell, ... Science 364 (6440), eaau0812, 2019 | 47 | 2019 |
Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5 D Zhang, W Tomisato, L Su, L Sun, JH Choi, Z Zhang, K Wang, X Zhan, ... Proceedings of the National Academy of Sciences 114 (26), E5197-E5206, 2017 | 26 | 2017 |
HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections L Sun, Z Jiang, VA Acosta-Rodriguez, M Berger, X Du, JH Choi, J Wang, ... Journal of Experimental Medicine 214 (11), 3263-3277, 2017 | 25 | 2017 |
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation T Misawa, JA SoRelle, JH Choi, T Yue, K Wang, W McAlpine, J Wang, ... Science immunology 5 (43), eaaz0085, 2020 | 18 | 2020 |
Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice K Wang, X Zhan, W McAlpine, Z Zhang, JH Choi, H Shi, T Misawa, T Yue, ... Proceedings of the National Academy of Sciences 116 (23), 11380-11389, 2019 | 17 | 2019 |
The class I myosin MYO1D binds to lipid and protects against colitis W McAlpine, K Wang, JH Choi, M San Miguel, SG McAlpine, J Russell, ... Disease models & mechanisms 11 (9), dmm035923, 2018 | 13 | 2018 |
Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning D Xu, S Lyon, CH Bu, S Hildebrand, JH Choi, X Zhong, A Liu, EE Turer, ... Proceedings of the National Academy of Sciences 118 (28), e2106786118, 2021 | 9 | 2021 |
Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40 D Zhang, T Yue, JH Choi, E Nair-Gill, X Zhong, K Wang, X Zhan, X Li, ... Nature immunology 20 (10), 1322-1334, 2019 | 8 | 2019 |
Dominant atopy risk mutations identified by mouse forward genetic analysis JA SoRelle, Z Chen, J Wang, T Yue, JH Choi, K Wang, X Zhong, ... Allergy 76 (4), 1095-1108, 2021 | 7 | 2021 |
A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis EE Turer, M San Miguel, K Wang, W McAlpine, F Ou, X Li, M Tang, Z Zang, ... Disease models & mechanisms 11 (12), dmm035451, 2018 | 6 | 2018 |
Identification of novel and potent synthetic TLR agonists Y Wang, L Su, M Morin, B Jones, L Whitby, M Surakattula, H Huang, H Shi, ... The Journal of Immunology 198 (1_Supplement), 129.3-129.3, 2017 | 1 | 2017 |
Structural characterization of TLRs with novel agonists L Su, Y Wang, MD Morin, BT Jones, LR Whitby, MMRP Surakattula, ... The Journal of Immunology 198 (1_Supplement), 129.4-129.4, 2017 | 1 | 2017 |