Glutamine metabolism is essential for human cytomegalovirus infection JW Chambers, TG Maguire, JC Alwine Journal of virology 84 (4), 1867-1873, 2010 | 261 | 2010 |
Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation JW Chambers, PV LoGrasso Journal of Biological Chemistry 286 (18), 16052-16062, 2011 | 228 | 2011 |
Atmospheric oxygen inhibits growth and differentiation of marrow‐derived mouse mesenchymal stem cells via a p53‐dependent mechanism: implications for long‐term culture expansion SV Boregowda, V Krishnappa, JW Chambers, PV Lograsso, WT Lai, ... Stem cells 30 (5), 975-987, 2012 | 122 | 2012 |
Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats JW Chambers, A Pachori, S Howard, S Iqbal, PV LoGrasso Journal of Biological Chemistry 288 (6), 4000-4011, 2013 | 91 | 2013 |
Small molecule c-jun-N-terminal kinase inhibitors protect dopaminergic neurons in a model of Parkinson’s disease JW Chambers, A Pachori, S Howard, M Ganno, D Hansen Jr, ... ACS chemical neuroscience 2 (4), 198-206, 2011 | 83 | 2011 |
Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo JW Chambers, S Howard, PV LoGrasso Journal of Biological Chemistry 288 (2), 1079-1087, 2013 | 81 | 2013 |
The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1 JW Chambers, ML Fowler, MT Morris, JC Morris Molecular and biochemical parasitology 158 (2), 202-207, 2008 | 73 | 2008 |
Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors T Kamenecka, R Jiang, X Song, D Duckett, W Chen, YY Ling, J Habel, ... Journal of medicinal chemistry 53 (1), 419-431, 2010 | 69 | 2010 |
Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1) JW Chambers, L Cherry, JD Laughlin, M Figuera-Losada, PV LoGrasso ACS chemical biology 6 (8), 808-818, 2011 | 56 | 2011 |
Activity of a Second Trypanosoma brucei Hexokinase Is Controlled by an 18-Amino-Acid C-Terminal Tail MT Morris, C DeBruin, Z Yang, JW Chambers, KS Smith, JC Morris Eukaryotic Cell 5 (12), 2014-2023, 2006 | 54 | 2006 |
Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme JW Chambers, MT Kearns, MT Morris, JC Morris Journal of Biological Chemistry 283 (22), 14963-14970, 2008 | 52 | 2008 |
Analysis of chemotherapeutic drug delivery at the single cell level using 3D-MSI-TOF-SIMS QP Vanbellingen, A Castellanos, M Rodriguez-Silva, I Paudel, ... Journal of The American Society for Mass Spectrometry 27 (12), 2033-2040, 2016 | 51 | 2016 |
Phosphoregulation on mitochondria: Integration of cell and organelle responses M Lucero, AE Suarez, JW Chambers CNS neuroscience & therapeutics 25 (7), 837-858, 2019 | 50 | 2019 |
Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1 HC Dodson, TA Lyda, JW Chambers, MT Morris, KA Christensen, ... Experimental parasitology 127 (2), 423-428, 2011 | 41 | 2011 |
A rapid and sensitive high-throughput screening method to identify compounds targeting protein–nucleic acids interactions N Alonso, R Guillen, JW Chambers, F Leng Nucleic acids research 43 (8), e52-e52, 2015 | 38 | 2015 |
Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity TP Chambers, L Santiesteban, D Gomez, JW Chambers Toxicology 382, 24-35, 2017 | 32 | 2017 |
Fluorescently labeled circular DNA molecules for DNA topology and topoisomerases M Gu, A Berrido, WG Gonzalez, J Miksovska, JW Chambers, F Leng Scientific reports 6 (1), 36006, 2016 | 21 | 2016 |
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases Y Feng, JW Chambers, S Iqbal, M Koenig, HJ Park, L Cherry, ... ACS chemical biology 8 (8), 1747-1754, 2013 | 20 | 2013 |
A trivalent approach for determining in vitro toxicology: Examination of oxime K027 A Prado, GA Petroianu, DE Lorke, JW Chambers Journal of Applied Toxicology 35 (2), 219-227, 2015 | 14 | 2015 |
Kinetic study of DNA topoisomerases by supercoiling-dependent fluorescence quenching Y Wang, S Rakela, JW Chambers, ZC Hua, MT Muller, JL Nitiss, ... ACS omega 4 (19), 18413-18422, 2019 | 13 | 2019 |