Understand spiciness: mechanism of TRPV1 channel activation by capsaicin F Yang, J Zheng Protein & cell 8, 169-177, 2017 | 298 | 2017 |
Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel F Yang, X Xiao, W Cheng, W Yang, P Yu, Z Song, V Yarov-Yarovoy, ... Nature Chemical Biology 11 (7), 518-524, 2015 | 284 | 2015 |
Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties W Cheng, F Yang, CL Takanishi, J Zheng The Journal of general physiology 129 (3), 191-207, 2007 | 232 | 2007 |
Thermosensitive TRP channel pore turret is part of the temperature activation pathway F Yang, Y Cui, KW Wang, J Zheng Proceedings of the National Academy of Sciences 107 (15), 7083-7088, 2010 | 226 | 2010 |
Application of fluorescence resonance energy transfer in protein studies L Ma, F Yang, J Zheng Journal of molecular structure 1077, 87-100, 2014 | 137 | 2014 |
A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1 S Yang, F Yang, N Wei, J Hong, B Li, L Luo, M Rong, V Yarov-Yarovoy, ... Nature communications 6, 8297, 2015 | 134 | 2015 |
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations Y Cui, F Yang, X Cao, V Yarov-Yarovoy, KW Wang, J Zheng Journal of general physiology 139 (4), 273-283, 2012 | 116 | 2012 |
Subunit assembly of N-methyl-d-aspartate receptors analyzed by fluorescence resonance energy transfer S Qiu, Y Hua, F Yang, Y Chen, J Luo Journal of Biological Chemistry 280 (26), 24923-24930, 2005 | 110 | 2005 |
Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response W Cheng, F Yang, S Liu, CK Colton, C Wang, Y Cui, X Cao, MX Zhu, ... Journal of Biological Chemistry 287 (10), 7279-7288, 2012 | 90 | 2012 |
Molecular basis for heat desensitization of TRPV1 ion channels L Luo, Y Wang, B Li, L Xu, PM Kamau, J Zheng, F Yang, S Yang, R Lai Nature communications 10 (1), 2134, 2019 | 78 | 2019 |
Intracellular proton-mediated activation of TRPV3 channels accounts for the exfoliation effect of α-hydroxyl acids on keratinocytes X Cao, F Yang, J Zheng, KW Wang Journal of Biological Chemistry 287 (31), 25905-25916, 2012 | 76 | 2012 |
High temperature sensitivity is intrinsic to voltage-gated potassium channels F Yang, J Zheng Elife 3, e03255, 2014 | 75 | 2014 |
Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel L Xu, Y Han, X Chen, A Aierken, H Wang, X Lu, Z Zhao, P Liang, W Yang, ... Biophysical Journal 118 (3), 413a, 2020 | 71 | 2020 |
Histone deacetylase 3 couples mitochondria to drive IL-1β-dependent inflammation by configuring fatty acid oxidation Z Chi, S Chen, T Xu, W Zhen, W Yu, D Jiang, X Guo, Z Wang, K Zhang, ... Molecular cell 80 (1), 43-58. e7, 2020 | 70 | 2020 |
Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis JJ Wang, F Liu, F Yang, YZ Wang, X Qi, Y Li, Q Hu, MX Zhu, TL Xu Nature communications 11 (1), 475, 2020 | 70 | 2020 |
The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel F Yang, X Xiao, BH Lee, S Vu, W Yang, V Yarov-Yarovoy, J Zheng Nature communications 9 (1), 2879, 2018 | 69 | 2018 |
Direct gating of the TRPM2 channel by cADPR via specific interactions with the ADPR binding pocket P Yu, Z Liu, X Yu, P Ye, H Liu, X Xue, L Yang, Z Li, Y Wu, C Fang, YJ Zhao, ... Cell reports 27 (12), 3684-3695. e4, 2019 | 65 | 2019 |
Divalent cations activate TRPV1 through promoting conformational change of the extracellular region F Yang, L Ma, X Cao, KW Wang, J Zheng Journal of General Physiology 143 (1), 91-103, 2014 | 65 | 2014 |
Rational design and validation of a vanilloid-sensitive TRPV2 ion channel F Yang, S Vu, V Yarov-Yarovoy, J Zheng Proceedings of the National Academy of Sciences 113 (26), E3657-E3666, 2016 | 56 | 2016 |
Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold X Cao, L Ma, F Yang, KW Wang, J Zheng Journal of General Physiology 143 (1), 75-90, 2014 | 55 | 2014 |