The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques PC Kandalepas, KR Sadleir, WA Eimer, J Zhao, DA Nicholson, R Vassar Acta neuropathologica 126, 329-352, 2013 | 259 | 2013 |
Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease KR Sadleir, PC Kandalepas, V Buggia-Prévot, DA Nicholson, ... Acta neuropathologica 132, 235-256, 2016 | 254 | 2016 |
Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons DA Nicholson, R Trana, Y Katz, WL Kath, N Spruston, Y Geinisman Neuron 50 (3), 431-442, 2006 | 243 | 2006 |
Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments DA Nicholson, R Yoshida, RW Berry, M Gallagher, Y Geinisman Journal of Neuroscience 24 (35), 7648-7653, 2004 | 243 | 2004 |
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration S Lumayag, CE Haldin, NJ Corbett, KJ Wahlin, C Cowan, S Turturro, ... Proceedings of the National Academy of Sciences 110 (6), E507-E516, 2013 | 205 | 2013 |
Synapse distribution suggests a two-stage model of dendritic integration in CA1 pyramidal neurons Y Katz, V Menon, DA Nicholson, Y Geinisman, WL Kath, N Spruston Neuron 63 (2), 171-177, 2009 | 202 | 2009 |
Differences in the expression of AMPA and NMDA receptors between axospinous perforated and nonperforated synapses are related to the configuration and size of postsynaptic … O Ganeshina, RW Berry, RS Petralia, DA Nicholson, Y Geinisman Journal of Comparative Neurology 468 (1), 86-95, 2004 | 197 | 2004 |
Identification of TMEM230 mutations in familial Parkinson's disease HX Deng, Y Shi, Y Yang, KB Ahmeti, N Miller, C Huang, L Cheng, H Zhai, ... Nature genetics 48 (7), 733-739, 2016 | 196 | 2016 |
Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes … AS Lewis, SP Vaidya, CA Blaiss, Z Liu, TR Stoub, DH Brager, X Chen, ... Journal of Neuroscience 31 (20), 7424-7440, 2011 | 160 | 2011 |
Synapses with a segmented, completely partitioned postsynaptic density express more AMPA receptors than other axospinous synaptic junctions O Ganeshina, RW Berry, RS Petralia, DA Nicholson, Y Geinisman Neuroscience 125 (3), 615-623, 2004 | 139 | 2004 |
Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus KA Dougherty, DA Nicholson, L Diaz, EW Buss, KM Neuman, ... Journal of neurophysiology 109 (7), 1940-1953, 2013 | 110 | 2013 |
Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons KM Neuman, E Molina-Campos, TF Musial, AL Price, KJ Oh, ML Wolke, ... Brain structure and function 220, 3143-3165, 2015 | 105 | 2015 |
Aging-related hyperexcitability in CA3 pyramidal neurons is mediated by enhanced A-type K+ channel function and expression D Simkin, S Hattori, N Ybarra, TF Musial, EW Buss, H Richter, MM Oh, ... Journal of Neuroscience 35 (38), 13206-13218, 2015 | 97 | 2015 |
Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a P arkinson disease patient JH Kordower, CG Goetz, Y Chu, GM Halliday, DA Nicholson, TF Musial, ... Annals of neurology 81 (1), 46-57, 2017 | 89 | 2017 |
Developmental changes in eye-blink conditioning and neuronal activity in the cerebellar interpositus nucleus JH Freeman, DA Nicholson Journal of Neuroscience 20 (2), 813-819, 2000 | 88 | 2000 |
Neuronal BIN1 regulates presynaptic neurotransmitter release and memory consolidation P De Rossi, T Nomura, RJ Andrew, NY Masse, V Sampathkumar, ... Cell reports 30 (10), 3520-3535. e7, 2020 | 79 | 2020 |
Lesions of the perirhinal cortex impair sensory preconditioning in rats DA Nicholson, JH Freeman Jr Behavioural brain research 112 (1-2), 69-75, 2000 | 71 | 2000 |
Axospinous synaptic subtype‐specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 … DA Nicholson, Y Geinisman Journal of Comparative Neurology 512 (3), 399-418, 2009 | 66 | 2009 |
Addition of inhibition in the olivocerebellar system and the ontogeny of a motor memory DA Nicholson, JH Freeman Jr Nature neuroscience 6 (5), 532-537, 2003 | 66 | 2003 |
The dendrites of CA2 and CA1 pyramidal neurons differentially regulate information flow in the cortico-hippocampal circuit KV Srinivas, EW Buss, Q Sun, B Santoro, H Takahashi, DA Nicholson, ... Journal of Neuroscience 37 (12), 3276-3293, 2017 | 61 | 2017 |