MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition D Horiuchi, L Kusdra, NE Huskey, S Chandriani, ME Lenburg, ... Journal of Experimental Medicine 209 (4), 679-696, 2012 | 385 | 2012 |
TGF-β-induced activation of mTOR complex 2 drives epithelial–mesenchymal transition and cell invasion S Lamouille, E Connolly, JW Smyth, RJ Akhurst, R Derynck Journal of cell science 125 (5), 1259-1273, 2012 | 379 | 2012 |
Stromal cell–derived factor-1α is cardioprotective after myocardial infarction A Saxena, JE Fish, MD White, S Yu, JWP Smyth, RM Shaw, JM DiMaio, ... Circulation 117 (17), 2224-2231, 2008 | 297 | 2008 |
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium JW Smyth, TT Hong, D Gao, JM Vogan, BC Jensen, TS Fong, ... The Journal of clinical investigation 120 (1), 266-279, 2010 | 262 | 2010 |
BIN1 localizes the L-type calcium channel to cardiac T-tubules TT Hong, JW Smyth, D Gao, KY Chu, JM Vogan, TS Fong, BC Jensen, ... PLoS biology 8 (2), e1000312, 2010 | 259 | 2010 |
Autoregulation of connexin43 gap junction formation by internally translated isoforms JW Smyth, RM Shaw Cell reports 5 (3), 611-618, 2013 | 159 | 2013 |
BIN1 is reduced and Cav1. 2 trafficking is impaired in human failing cardiomyocytes TT Hong, JW Smyth, KY Chu, JM Vogan, TS Fong, BC Jensen, K Fang, ... Heart rhythm 9 (5), 812-820, 2012 | 159 | 2012 |
Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane JW Smyth, JM Vogan, PJ Buch, SS Zhang, TS Fong, TT Hong, RM Shaw Circulation research 110 (7), 978-989, 2012 | 139 | 2012 |
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His–Purkinje network SS Zhang, KH Kim, A Rosen, JW Smyth, R Sakuma, P Delgado-Olguín, ... Proceedings of the National Academy of Sciences 108 (33), 13576-13581, 2011 | 132 | 2011 |
The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation R Veeraraghavan, GS Hoeker, A Alvarez-Laviada, D Hoagland, X Wan, ... Elife 7, e37610, 2018 | 103 | 2018 |
A 14‐3‐3 mode‐1 binding motif initiates gap junction internalization during acute cardiac ischemia JW Smyth, SS Zhang, JM Sanchez, S Lamouille, JM Vogan, GG Hesketh, ... Traffic 15 (6), 684-699, 2014 | 96 | 2014 |
The pericyte microenvironment during vascular development LB Payne, H Zhao, CC James, J Darden, D McGuire, S Taylor, JW Smyth, ... Microcirculation 26 (8), e12554, 2019 | 58 | 2019 |
Altered translation initiation of Gja1 limits gap junction formation during epithelial–mesenchymal transition CC James, MJ Zeitz, PJ Calhoun, S Lamouille, JW Smyth Molecular biology of the cell 29 (7), 797-808, 2018 | 48 | 2018 |
The gap junction life cycle JW Smyth, RM Shaw Heart Rhythm 9 (1), 151-153, 2012 | 48 | 2012 |
Treatment of rapidly growing K-BALB and CT26 mouse tumours using Semliki Forest virus and its derived vector JWP Smyth, MN Fleeton, BJ Sheahan, GJ Atkins Gene Therapy 12 (2), 147-159, 2005 | 45 | 2005 |
Development of PLGA nanoparticles for sustained release of a connexin43 mimetic peptide to target glioblastoma cells R Roberts, JW Smyth, J Will, P Roberts, CL Grek, GS Ghatnekar, Z Sheng, ... Materials Science and Engineering: C 108, 110191, 2020 | 41 | 2020 |
Progression-mediated changes in mitochondrial morphology promotes adaptation to hypoxic peritoneal conditions in serous ovarian cancer JP Grieco, ME Allen, JB Perry, Y Wang, Y Song, A Rohani, SLE Compton, ... Frontiers in oncology 10, 600113, 2021 | 39 | 2021 |
Extracellular sodium dependence of the conduction velocity-calcium relationship: evidence of ephaptic self-attenuation S George, M Bonakdar, M Zeitz, R Davalos, J Smyth, S Poelzing Biophysical Journal 110 (3), 30a-31a, 2016 | 39 | 2016 |
Forward trafficking of ion channels: what the clinician needs to know JW Smyth, RM Shaw Heart rhythm 7 (8), 1135-1140, 2010 | 39 | 2010 |
Alternative mechanisms of translation initiation: An emerging dynamic regulator of the proteome in health and disease CC James, JW Smyth Life sciences 212, 138-144, 2018 | 38 | 2018 |