标题/作者	年份
Search-and-replace genome editing without double-strand breaks or donor DNA AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ... Nature 576 (7785), 149-157	2019
Adeno-associated virus vector as a platform for gene therapy delivery D Wang, PWL Tai, G Gao Nature reviews Drug discovery 18 (5), 358-378	2019
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors AV Anzalone, LW Koblan, DR Liu Nature biotechnology 38 (7), 824-844	2020
The expanding regulatory mechanisms and cellular functions of circular RNAs LL Chen Nature reviews Molecular cell biology 21 (8), 475-490	2020
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants RT Walton, KA Christie, MN Whittaker, BP Kleinstiver Science 368 (6488), 290-296	2020
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos E Zuo, Y Sun, W Wei, T Yuan, W Ying, H Sun, L Yuan, LM Steinmetz, Y Li, ... Science 364 (6437), 289-292	2019
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice S Jin, Y Zong, Q Gao, Z Zhu, Y Wang, P Qin, C Liang, D Wang, JL Qiu, ... Science 364 (6437), 292-295	2019
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity MF Richter, KT Zhao, E Eton, A Lapinaite, GA Newby, BW Thuronyi, ... Nature biotechnology 38 (7), 883-891	2020
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung Nature 569 (7756), 433-437	2019
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing BY Mok, MH de Moraes, J Zeng, DE Bosch, AV Kotrys, A Raguram, ... Nature 583 (7817), 631-637	2020
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis C Zhou, Y Sun, R Yan, Y Liu, E Zuo, C Gu, L Han, Y Wei, X Hu, R Zeng, ... Nature 571 (7764), 275-278	2019
Directed evolution of adenine base editors with increased activity and therapeutic application NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ... Nature biotechnology 38 (7), 892-900	2020
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells IC Kurt, R Zhou, S Iyer, SP Garcia, BR Miller, LM Langner, J Grünewald, ... Nature biotechnology 39 (1), 41-46	2021
A cytosine deaminase for programmable single-base RNA editing OO Abudayyeh, JS Gootenberg, B Franklin, J Koob, MJ Kellner, A Ladha, ... Science 365 (6451), 382-386	2019
The emerging and uncultivated potential of CRISPR technology in plant science Y Zhang, AA Malzahn, S Sretenovic, Y Qi Nature Plants 5 (8), 778-794	2019
CRISPR/Cas system: recent advances and future prospects for genome editing H Manghwar, K Lindsey, X Zhang, S Jin Trends in plant science 24 (12), 1102-1125	2019
CRISPR-based therapeutic genome editing: strategies and in vivo delivery by AAV vectors D Wang, F Zhang, G Gao Cell 181 (1), 136-150	2020
Continuous evolution of base editors with expanded target compatibility and improved activity BW Thuronyi, LW Koblan, JM Levy, WH Yeh, C Zheng, GA Newby, ... Nature biotechnology 37 (9), 1070-1079	2019
Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors JL Doman, A Raguram, GA Newby, DR Liu Nature biotechnology 38 (5), 620-628	2020
Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses JM Levy, WH Yeh, N Pendse, JR Davis, E Hennessey, R Butcher, ... Nature biomedical engineering 4 (1), 97-110	2020

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