A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome J Cools, DJ DeAngelo, J Gotlib, EH Stover, RD Legare, J Cortes, J Kutok, ... New England Journal of Medicine 348 (13), 1201-1214, 2003 | 2091 | 2003 |
Allergen immunotherapy: a practice parameter third update L Cox, H Nelson, R Lockey, C Calabria, T Chacko, I Finegold, M Nelson, ... Journal of Allergy and Clinical Immunology 127 (1), S1-S55, 2011 | 1357 | 2011 |
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides S Sur, JS Wild, BK Choudhury, N Sur, R Alam, DM Klinman The Journal of Immunology 162 (10), 6284-6293, 1999 | 515 | 1999 |
RANTES is a chemotactic and activating factor for human eosinophils. R Alam, S Stafford, P Forsythe, R Harrison, D Faubion, MA Lett-Brown, ... Journal of immunology (Baltimore, Md.: 1950) 150 (8), 3442-3448, 1993 | 477 | 1993 |
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation I Boldogh, A Bacsi, BK Choudhury, N Dharajiya, R Alam, TK Hazra, ... The Journal of clinical investigation 115 (8), 2169-2179, 2005 | 396 | 2005 |
Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients. R Alam, J York, M Boyars, S Stafford, JA Grant, J Lee, P Forsythe, T Sim, ... American journal of respiratory and critical care medicine 153 (4), 1398-1404, 1996 | 384 | 1996 |
IFN-γ-inducing factor (IL-18) increases allergic sensitization, serum IgE, Th2 cytokines, and airway eosinophilia in a mouse model of allergic asthma JS Wild, A Sigounas, N Sur, MS Siddiqui, R Alam, M Kurimoto, S Sur The Journal of Immunology 164 (5), 2701-2710, 2000 | 371 | 2000 |
Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases: Presented in part at the annual meetings … GT Kampen, S Stafford, T Adachi, T Jinquan, S Quan, JA Grant, PS Skov, ... Blood, The Journal of the American Society of Hematology 95 (6), 1911-1917, 2000 | 366 | 2000 |
Cell-specific expression of RANTES, MCP-1, and MIP-1α by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus B Olszewska-Pazdrak, A Casola, T Saito, R Alam, SE Crowe, F Mei, ... Journal of virology 72 (6), 4756-4764, 1998 | 324 | 1998 |
Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma C Irvin, I Zafar, J Good, D Rollins, C Christianson, MM Gorska, RJ Martin, ... Journal of allergy and clinical immunology 134 (5), 1175-1186. e7, 2014 | 312 | 2014 |
Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33 CA Christianson, NP Goplen, I Zafar, C Irvin, JT Good Jr, DR Rollins, ... Journal of Allergy and Clinical Immunology 136 (1), 59-68. e14, 2015 | 288 | 2015 |
Macrophage inflammatory protein-1 alpha activates basophils and mast cells. R Alam, PA Forsythe, S Stafford, MA Lett-Brown, JA Grant The Journal of experimental medicine 176 (3), 781-786, 1992 | 263 | 1992 |
The mechanism of IL-5 signal transduction T Adachi, R Alam American Journal of Physiology-Cell Physiology 275 (3), C623-C633, 1998 | 244 | 1998 |
Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: the role of thymic stromal lymphopoietin S Liu, M Verma, L Michalec, W Liu, A Sripada, D Rollins, J Good, Y Ito, ... Journal of Allergy and Clinical Immunology 141 (1), 257-268. e6, 2018 | 232 | 2018 |
IL-13 released by and localized in human basophils. H Li, TC Sim, R Alam Journal of immunology (Baltimore, Md.: 1950) 156 (12), 4833-4838, 1996 | 219 | 1996 |
Transforming growth factor beta abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. R Alam, P Forsythe, S Stafford, Y Fukuda The Journal of experimental medicine 179 (3), 1041-1045, 1994 | 218 | 1994 |
Respiratory syncytial virus induces selective production of the chemokine RANTES by upper airway epithelial cells T Saito, RW Deskin, A Casola, H Haeberle, B Olszewska, PB Ernst, ... Journal of Infectious Diseases 175 (3), 497-504, 1997 | 213 | 1997 |
Monocyte chemotactic and activating factor is a potent histamine-releasing factor for basophils. R Alam, MA Lett-Brown, PA Forsythe, DJ Anderson-Walters, C Kenamore, ... The Journal of clinical investigation 89 (3), 723-728, 1992 | 212 | 1992 |
Biologic activities of IL-1 and its role in human disease DM Essayan, CC Fox, F Levi-Schaffer, R Alam, LJ Rosenwasser Journal of allergy and clinical immunology 102 (3), 344-350, 1998 | 200 | 1998 |
Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation K Pazdrak, B Olszewska-Pazdrak, S Stafford, RP Garofalo, R Alam The Journal of experimental medicine 188 (3), 421-429, 1998 | 190 | 1998 |