关注
R. Esala P. Chandrasena
R. Esala P. Chandrasena
CDPH
在 cdph.ca.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cytochrome P450 compound I
M Newcomb, R Zhang, REP Chandrasena, JA Halgrimson, JH Horner, ...
Journal of the American Chemical Society 128 (14), 4580-4581, 2006
1802006
Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity
Z Qin, I Kastrati, REP Chandrasena, H Liu, P Yao, PA Petukhov, JL Bolton, ...
Journal of Medicinal Chemistry 50 (11), 2682-2692, 2007
1752007
Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes
REP Chandrasena, KP Vatsis, MJ Coon, PF Hollenberg, M Newcomb
Journal of the American Chemical Society 126 (1), 115-126, 2004
1302004
Kinetic isotope effects implicate two electrophilic oxidants in cytochrome P450-catalyzed hydroxylations
M Newcomb, D Aebisher, R Shen, REP Chandrasena, PF Hollenberg, ...
Journal of the American Chemical Society 125 (20), 6064-6065, 2003
1012003
Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection
T Dunlap, REP Chandrasena, Z Wang, V Sinha, Z Wang, GRJ Thatcher
Chemical research in toxicology 20 (12), 1903-1912, 2007
732007
Highly reactive electrophilic oxidants in cytochrome P450 catalysis
M Newcomb, REP Chandrasena
Biochemical and biophysical research communications 338 (1), 394-403, 2005
732005
Hops (Humulus lupulus) Inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Malignant Transformation in Human Mammary Epithelial cells (MCF-10A)
LP Hemachandra, P Madhubhani, R Chandrasena, P Esala, SN Chen, ...
Cancer prevention research 5 (1), 73-81, 2012
672012
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens
Z Wang, ER Chandrasena, Y Yuan, K Peng, RB van Breemen, ...
Chemical research in toxicology 23 (8), 1365-1373, 2010
622010
Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens
HY Kim, J Sohn, GT Wijewickrama, P Edirisinghe, T Gherezghiher, ...
Bioorganic & medicinal chemistry 18 (2), 809-821, 2010
482010
Proteomic and Mass Spectroscopic Quantitation of Protein S-Nitrosation Differentiates NO-Donors
V Sinha, GT Wijewickrama, REP Chandrasena, H Xu, PD Edirisinghe, ...
ACS chemical biology 5 (7), 667-680, 2010
472010
Formation of Compound I by photo-oxidation of Compound II
R Zhang, REP Chandrasena, E Martinez, JH Horner, M Newcomb
Organic letters 7 (6), 1193-1195, 2005
432005
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality
T Dunlap, SO Abdul-Hay, REP Chandrasena, GK Hagos, V Sinha, ...
Nitric Oxide 19 (2), 115-124, 2008
412008
Problematic Detoxification of Estrogen Quinones by NAD(P)H-Dependent Quinone Oxidoreductase and Glutathione-S-transferase
REP Chandrasena, PD Edirisinghe, JL Bolton, GRJ Thatcher
Chemical research in toxicology 21 (7), 1324-1329, 2008
392008
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors
IT Schiefer, S Tapadar, V Litosh, M Siklos, R Scism, GT Wijewickrama, ...
Journal of medicinal chemistry 56 (15), 6054-6068, 2013
382013
Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention
GK Hagos, SO Abdul-Hay, J Sohn, PD Edirisinghe, REP Chandrasena, ...
Molecular pharmacology 74 (5), 1381-1391, 2008
252008
NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor
S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ...
ACS medicinal chemistry letters 2 (9), 656-661, 2011
242011
Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane
M Newcomb, REP Chandrasena, DSP Lansakara-P, HY Kim, SJ Lippard, ...
The Journal of organic chemistry 72 (4), 1121-1127, 2007
212007
Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol
BT Michalsen, TB Gherezghiher, J Choi, REP Chandrasena, Z Qin, ...
Chemical Research in Toxicology 25 (7), 1472-1483, 2012
162012
II; Horner, JH; Newcomb, M
R Zhang, REP Chandrasena, E Martinez
Org. Lett 7, 1193, 2005
162005
Organic Chemical Contaminants in Water System Infrastructure Following Wildfire
ACS EST Water 2 (2), 357–366, 2022
15*2022
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