Cytochrome P450 compound I M Newcomb, R Zhang, REP Chandrasena, JA Halgrimson, JH Horner, ... Journal of the American Chemical Society 128 (14), 4580-4581, 2006 | 180 | 2006 |
Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity Z Qin, I Kastrati, REP Chandrasena, H Liu, P Yao, PA Petukhov, JL Bolton, ... Journal of Medicinal Chemistry 50 (11), 2682-2692, 2007 | 175 | 2007 |
Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes REP Chandrasena, KP Vatsis, MJ Coon, PF Hollenberg, M Newcomb Journal of the American Chemical Society 126 (1), 115-126, 2004 | 130 | 2004 |
Kinetic isotope effects implicate two electrophilic oxidants in cytochrome P450-catalyzed hydroxylations M Newcomb, D Aebisher, R Shen, REP Chandrasena, PF Hollenberg, ... Journal of the American Chemical Society 125 (20), 6064-6065, 2003 | 101 | 2003 |
Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection T Dunlap, REP Chandrasena, Z Wang, V Sinha, Z Wang, GRJ Thatcher Chemical research in toxicology 20 (12), 1903-1912, 2007 | 73 | 2007 |
Highly reactive electrophilic oxidants in cytochrome P450 catalysis M Newcomb, REP Chandrasena Biochemical and biophysical research communications 338 (1), 394-403, 2005 | 73 | 2005 |
Hops (Humulus lupulus) Inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Malignant Transformation in Human Mammary Epithelial cells (MCF-10A) LP Hemachandra, P Madhubhani, R Chandrasena, P Esala, SN Chen, ... Cancer prevention research 5 (1), 73-81, 2012 | 67 | 2012 |
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens Z Wang, ER Chandrasena, Y Yuan, K Peng, RB van Breemen, ... Chemical research in toxicology 23 (8), 1365-1373, 2010 | 62 | 2010 |
Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens HY Kim, J Sohn, GT Wijewickrama, P Edirisinghe, T Gherezghiher, ... Bioorganic & medicinal chemistry 18 (2), 809-821, 2010 | 48 | 2010 |
Proteomic and Mass Spectroscopic Quantitation of Protein S-Nitrosation Differentiates NO-Donors V Sinha, GT Wijewickrama, REP Chandrasena, H Xu, PD Edirisinghe, ... ACS chemical biology 5 (7), 667-680, 2010 | 47 | 2010 |
Formation of Compound I by photo-oxidation of Compound II R Zhang, REP Chandrasena, E Martinez, JH Horner, M Newcomb Organic letters 7 (6), 1193-1195, 2005 | 43 | 2005 |
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality T Dunlap, SO Abdul-Hay, REP Chandrasena, GK Hagos, V Sinha, ... Nitric Oxide 19 (2), 115-124, 2008 | 41 | 2008 |
Problematic Detoxification of Estrogen Quinones by NAD(P)H-Dependent Quinone Oxidoreductase and Glutathione-S-transferase REP Chandrasena, PD Edirisinghe, JL Bolton, GRJ Thatcher Chemical research in toxicology 21 (7), 1324-1329, 2008 | 39 | 2008 |
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors IT Schiefer, S Tapadar, V Litosh, M Siklos, R Scism, GT Wijewickrama, ... Journal of medicinal chemistry 56 (15), 6054-6068, 2013 | 38 | 2013 |
Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention GK Hagos, SO Abdul-Hay, J Sohn, PD Edirisinghe, REP Chandrasena, ... Molecular pharmacology 74 (5), 1381-1391, 2008 | 25 | 2008 |
NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ... ACS medicinal chemistry letters 2 (9), 656-661, 2011 | 24 | 2011 |
Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane M Newcomb, REP Chandrasena, DSP Lansakara-P, HY Kim, SJ Lippard, ... The Journal of organic chemistry 72 (4), 1121-1127, 2007 | 21 | 2007 |
Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol BT Michalsen, TB Gherezghiher, J Choi, REP Chandrasena, Z Qin, ... Chemical Research in Toxicology 25 (7), 1472-1483, 2012 | 16 | 2012 |
II; Horner, JH; Newcomb, M R Zhang, REP Chandrasena, E Martinez Org. Lett 7, 1193, 2005 | 16 | 2005 |
Organic Chemical Contaminants in Water System Infrastructure Following Wildfire ACS EST Water 2 (2), 357–366, 2022 | 15* | 2022 |