Mitragynine/corynantheidine pseudoindoxyls as opioid analgesics with mu agonism and delta antagonism, which do not recruit β-arrestin-2 A Váradi, GF Marrone, TC Palmer, A Narayan, MR Szabó, V Le Rouzic, ... Journal of medicinal chemistry 59 (18), 8381-8397, 2016 | 292 | 2016 |
Flap opening mechanism of HIV-1 protease G Tóth, A Borics Journal of Molecular Graphics and Modelling 24 (6), 465-474, 2006 | 91 | 2006 |
A Penicillium chrysogenum-based expression system for the production of small, cysteine-rich antifungal proteins for structural and functional analyses C Sonderegger, L Galgóczy, S Garrigues, Á Fizil, A Borics, P Manzanares, ... Microbial Cell Factories 15, 1-14, 2016 | 66 | 2016 |
Closing of the flaps of HIV-1 protease induced by substrate binding: a model of a flap closing mechanism in retroviral aspartic proteases G Tóth, A Borics Biochemistry 45 (21), 6606-6614, 2006 | 62 | 2006 |
New endomorphin analogues containing alicyclic β-amino acids: Influence on bioactive conformation and pharmacological profile A Keresztes, M Szucs, A Borics, KE Kövér, E Forro, F Fülöp, ... Journal of Medicinal Chemistry 51 (14), 4270-4279, 2008 | 54 | 2008 |
Synthesis of carfentanil amide opioids using the Ugi multicomponent reaction A Váradi, TC Palmer, N Haselton, D Afonin, JJ Subrath, V Le Rouzic, ... ACS chemical neuroscience 6 (9), 1570-1577, 2015 | 52 | 2015 |
Recent advances in endomorphin engineering A Keresztes, A Borics, G Tóth ChemMedChem 5 (8), 1176-1196, 2010 | 50 | 2010 |
Efficient production and characterization of the novel and highly active antifungal protein AfpB from Penicillium digitatum S Garrigues, M Gandía, C Popa, A Borics, F Marx, M Coca, JF Marcos, ... Scientific reports 7 (1), 14663, 2017 | 48 | 2017 |
NFAP2, a novel cysteine-rich anti-yeast protein from Neosartorya fischeri NRRL 181: isolation and characterization L Tóth, Z Kele, A Borics, LG Nagy, G Váradi, M Virágh, M Takó, ... Amb Express 6, 1-13, 2016 | 44 | 2016 |
Structural comparison of μ-opioid receptor selective peptides confirmed four parameters of bioactivity A Borics, G Tóth Journal of Molecular Graphics and Modelling 28 (6), 495-505, 2010 | 43 | 2010 |
Endomorphin-2 with a β-turn backbone constraint retains the potent μ-opioid receptor agonist properties C Tömböly, S Ballet, D Feytens, KE Kövér, A Borics, S Lovas, ... Journal of medicinal chemistry 51 (1), 173-177, 2008 | 40 | 2008 |
Design, synthesis, pharmacological evaluation, and structure− activity study of novel endomorphin analogues with multiple structural modifications JR Mallareddy, A Borics, A Keresztes, KE Kövér, D Tourwé, G Tóth Journal of medicinal chemistry 54 (5), 1462-1472, 2011 | 37 | 2011 |
The evolutionary conserved γ-core motif influences the anti-Candida activity of the Penicillium chrysogenum antifungal protein PAF C Sonderegger, G Váradi, L Galgóczy, S Kocsubé, W Posch, S Dubrac, ... Frontiers in Microbiology 9, 393957, 2018 | 33 | 2018 |
Anti-candidal activity and functional mapping of recombinant and synthetic Neosartorya fischeri antifungal protein 2 (NFAP2) L Tóth, G Váradi, A Borics, G Batta, Á Vendrinszky, GK Tóth, C Vágvölgyi, ... Frontiers in Microbiology 9, 350087, 2018 | 33 | 2018 |
In Vivo Applicability of Neosartorya fischeri Antifungal Protein 2 (NFAP2) in Treatment of Vulvovaginal Candidiasis R Kovács, J Holzknecht, Z Hargitai, C Papp, A Farkas, A Borics, L Tóth, ... Antimicrobial Agents and Chemotherapy 63 (2), 10.1128/aac. 01777-18, 2019 | 29 | 2019 |
Fourier transform vibrational circular dichroism as a decisive tool for conformational studies of peptides containing tyrosyl residues A Borics, RF Murphy, S Lovas Biopolymers: Original Research on Biomolecules 72 (1), 21-24, 2003 | 29 | 2003 |
Mapping and identification of antifungal peptides in the putative antifungal protein AfpB from the filamentous fungus Penicillium digitatum S Garrigues, F Marx, P Manzanares, JF Marcos Frontiers in Microbiology 8, 255289, 2017 | 26 | 2017 |
Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity L Galgóczy, A Borics, M Virágh, H Ficze, G Váradi, Z Kele, F Marx Scientific Reports 7 (1), 1963, 2017 | 22 | 2017 |
Biofungicidal potential of Neosartorya (Aspergillus) fischeri antifungal protein NFAP and novel synthetic γ-core peptides L Tóth, G Váradi, É Boros, A Borics, H Ficze, I Nagy, GK Tóth, G Rákhely, ... Frontiers in Microbiology 11, 529426, 2020 | 20 | 2020 |
Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor … O Dömötör, K Pelivan, A Borics, BK Keppler, CR Kowol, ÉA Enyedy Journal of Pharmaceutical and Biomedical Analysis 154, 321-331, 2018 | 20 | 2018 |