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| TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis J Sreedharan, IP Blair, VB Tripathi, X Hu, C Vance, B Rogelj, S Ackerley, ... Science 319 (5870), 1668-1672, 2008 | 2799 | 2008 |
| Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. L Lacomblez, G Bensimon, PN Leigh, P Guillet, V Meininger Lancet (London, England) 347 (9013), 1425-1431, 1996 | 1477 | 1996 |
| Amyotrophic lateral sclerosis LC Wijesekera, P Nigel Leigh Orphanet journal of rare diseases 4, 1-22, 2009 | 1405 | 2009 |
| Fronto-striatal cognitive deficits at different stages of Parkinson's disease AM Owen, M James, PN Leigh, BA Summers, CD Marsden, NP Quinn, ... Brain 115 (6), 1727-1751, 1992 | 1115 | 1992 |
| Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study MR Turner, A Cagnin, FE Turkheimer, CCJ Miller, CE Shaw, DJ Brooks, ... Neurobiology of disease 15 (3), 601-609, 2004 | 782 | 2004 |
| Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis MJ Strong, GM Grace, M Freedman, C Lomen-Hoerth, S Woolley, ... Amyotrophic Lateral Sclerosis 10 (3), 131-146, 2009 | 620 | 2009 |
| Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 534 | 2016 |
| Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease CAD Smith, CR Wolf, AC Gough, NK Spurr, PN Leigh, BA Summers, ... The Lancet 339 (8806), 1375-1377, 1992 | 526 | 1992 |
| Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS) S Abrahams, PN Leigh, A Harvey, GN Vythelingum, D Grise, LH Goldstein Neuropsychologia 38 (6), 734-747, 2000 | 496 | 2000 |
| Biomarkers in amyotrophic lateral sclerosis MR Turner, MC Kiernan, PN Leigh, K Talbot The Lancet Neurology 8 (1), 94-109, 2009 | 493 | 2009 |
| Diffusion tensor MRI assesses corticospinal tract damage in ALS CM Ellis, A Simmons, DK Jones, J Bland, JM Dawson, MA Horsfield, ... Neurology 53 (5), 1051-1051, 1999 | 488 | 1999 |
| Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis A Al-Chalabi, PM Andersen, P Nilsson, B Chioza, JL Andersson, C Russ, ... Human molecular genetics 8 (2), 157-164, 1999 | 468 | 1999 |
| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 466 | 2007 |
| Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis RA Lyall, N Donaldson, MI Polkey, PN Leigh, J Moxham Brain 124 (10), 2000-2013, 2001 | 449 | 2001 |
| Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis: morphology, distribution, and specificity PN Leigh, H Whitwell, O Garofalo, J Buller, M Swash, JE Martin, JM Gallo, ... Brain 114 (2), 775-788, 1991 | 414 | 1991 |
| Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis MA Van Es, JH Veldink, CGJ Saris, HM Blauw, PWJ van Vught, A Birve, ... Nature genetics 41 (10), 1083-1087, 2009 | 400 | 2009 |
| Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction. TW Robbins, M James, AM Owen, KW Lange, AJ Lees, PN Leigh, ... Journal of Neurology, Neurosurgery & Psychiatry 57 (1), 79-88, 1994 | 381 | 1994 |
| A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis GD Borasio, W Robberecht, PN Leigh, J Emile, RJ Guiloff, F Jerusalem, ... Neurology 51 (2), 583-586, 1998 | 380 | 1998 |
| Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study G Bensimon, A Ludolph, Y Agid, M Vidailhet, C Payan, PN Leigh, ... Brain 132 (1), 156-171, 2009 | 376 | 2009 |
ammar al-chalabiProfessor of Neurology and Complex Disease Genetics, King's College London在 kcl.ac.uk 的电子邮件经过验证
