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Qi Zhang
Qi Zhang
在 mdanderson.org 的电子邮件经过验证
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引用次数
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年份
An inhibitor of oxidative phosphorylation exploits cancer vulnerability
JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ...
Nature medicine 24 (7), 1036-1046, 2018
5922018
Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
CD DiNardo, IS Tiong, A Quaglieri, S MacRaild, S Loghavi, FC Brown, ...
Blood 135 (11), 791-803, 2020
3652020
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
S Khan, X Zhang, D Lv, Q Zhang, Y He, P Zhang, X Liu, D Thummuri, ...
Nature medicine 25 (12), 1938-1947, 2019
3082019
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models
L Han, Q Zhang, M Dail, C Shi, A Cavazos, VR Ruvolo, Y Zhao, E Kim, ...
Haematologica 105 (3), 697, 2020
822020
Disruption of Wnt/β-catenin exerts antileukemia activity and synergizes with FLT3 inhibition in FLT3-mutant acute myeloid leukemia
X Jiang, PY Mak, H Mu, W Tao, DH Mak, S Kornblau, Q Zhang, P Ruvolo, ...
Clinical Cancer Research 24 (10), 2417-2429, 2018
662018
Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
RS Mali, Q Zhang, RA DeFilippis, A Cavazos, VM Kuruvilla, J Raman, ...
Haematologica 106 (4), 1034, 2021
652021
Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD
T Yuan, Y Yang, J Chen, W Li, Q Zhang, Y Mi, RS Goswami, JQ You, ...
Leukemia 31 (11), 2355-2364, 2017
562017
A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies
DC Phillips, S Jin, GP Gregory, Q Zhang, J Xue, X Zhao, J Chen, Y Tong, ...
Leukemia 34 (6), 1646-1657, 2020
502020
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity
D Lv, P Pal, X Liu, Y Jia, D Thummuri, P Zhang, W Hu, J Pei, Q Zhang, ...
Nature communications 12 (1), 6896, 2021
462021
Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell …
Q Zhang, C Shi, L Han, N Jain, KG Roberts, H Ma, T Cai, A Cavazos, ...
Oncotarget 9 (8), 8027, 2018
392018
Antileukemia efficacy and mechanisms of action of SL-101, a novel anti-CD123 antibody conjugate, in acute myeloid leukemia
L Han, JL Jorgensen, C Brooks, C Shi, Q Zhang, GM Nogueras González, ...
Clinical Cancer Research 23 (13), 3385-3395, 2017
362017
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia
Q Zhang, B Riley-Gillis, L Han, Y Jia, A Lodi, H Zhang, S Ganesan, R Pan, ...
Signal transduction and targeted therapy 7 (1), 51, 2022
352022
MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/progenitor cells
Z Zeng, RY Wang, YH Qiu, DH Mak, K Coombes, SY Yoo, Q Zhang, ...
Oncotarget 7 (34), 55083, 2016
322016
Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition
K Saito, Q Zhang, H Yang, K Yamatani, T Ai, V Ruvolo, N Baran, T Cai, ...
Blood Advances 5 (20), 4233-4255, 2021
282021
Interim analysis of phase II study of venetoclax with 10-day decitabine (DEC10-VEN) in acute myeloid leukemia and myelodysplastic syndrome
A Maiti, CD DiNardo, JE Cortes, G Borthakur, N Pemmaraju, CB Benton, ...
Blood 132, 286, 2018
232018
IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia
Q Fang, X Zhao, Q Li, Y Li, K Liu, K Tang, Y Wang, B Liu, M Wang, H Xing, ...
Leukemia & Lymphoma 58 (1), 127-137, 2017
202017
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials
TA Yap, N Daver, M Mahendra, J Zhang, C Kamiya-Matsuoka, ...
Nature Medicine, 1-12, 2023
192023
Ten-day decitabine with venetoclax (DEC10-VEN) in acute myeloid leukemia: updated results of a phase II trial
A Maiti, CD DiNardo, CR Rausch, JE Cortes, N Pemmaraju, NG Daver, ...
Blood 134, 2637, 2019
192019
Prognostic significance of copy number alterations detected by multi‑link probe amplification of multiple genes in adult acute lymphoblastic leukemia
Q Fang, T Yuan, Y Li, J Feng, X Gong, Q Li, X Zhao, K Liu, K Tang, Z Tian, ...
Oncology Letters 15 (4), 5359-5367, 2018
162018
Mitochondrial OxPhos as survival mechanism of minimal residual AML cells after induction chemotherapy: survival benefit by complex I inhibition with IACS-010759
L Han, A Cavazos, N Baran, Q Zhang, VM Kuruvilla, JP Gay, N Feng, ...
Blood 134, 5161, 2019
142019
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