Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference Y Huang, DJ McCarthy, O Stegle Genome biology 20, 1-12, 2019 | 110 | 2019 |
Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast V Aslanzadeh, Y Huang, G Sanguinetti, JD Beggs Genome research 28 (2), 203-213, 2018 | 87 | 2018 |
BRIE: transcriptome-wide splicing quantification in single cells Y Huang, G Sanguinetti Genome biology 18, 1-11, 2017 | 80 | 2017 |
Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling JD Barrass, JEA Reid, Y Huang, RD Hector, G Sanguinetti, JD Beggs, ... Genome biology 16, 1-17, 2015 | 74 | 2015 |
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes DJ McCarthy, R Rostom, Y Huang, DJ Kunz, P Danecek, MJ Bonder, ... Nature Methods 17 (4), 414-421, 2020 | 48* | 2020 |
Cellsnp-lite: an efficient tool for genotyping single cells X Huang, Y Huang Bioinformatics 37 (23), 4569-4571, 2021 | 38 | 2021 |
Systematic characterization and prediction of post-translational modification cross-talk Y Huang, B Xu, X Zhou, Y Li, M Lu, R Jiang, T Li Molecular & Cellular Proteomics 14 (3), 761-770, 2015 | 36 | 2015 |
Naive pluripotent stem cells exhibit phenotypic variability that is driven by genetic variation D Ortmann, S Brown, A Czechanski, S Aydin, D Muraro, Y Huang, ... Cell Stem Cell 27 (3), 470-481. e6, 2020 | 31 | 2020 |
BRIE2: computational identification of splicing phenotypes from single-cell transcriptomic experiments Y Huang, G Sanguinetti Genome biology 22 (1), 1-15, 2021 | 19* | 2021 |
Representation learning of RNA velocity reveals robust cell transitions C Qiao, Y Huang Proceedings of the National Academy of Sciences 118 (49), e2105859118, 2021 | 17 | 2021 |
Systematic characterization and prediction of post-translational modification cross-talk between proteins R Huang, Y Huang, Y Guo, S Ji, M Lu, T Li Bioinformatics 35 (15), 2626-2633, 2019 | 11 | 2019 |
Statistical modeling of isoform splicing dynamics from RNA-seq time series data Y Huang, G Sanguinetti Bioinformatics 32 (19), 2965-2972, 2016 | 11 | 2016 |
UniTVelo: temporally unified RNA velocity reinforces single-cell trajectory inference M Gao, C Qiao, Y Huang Nature Communications 13 (1), 6586, 2022 | 10 | 2022 |
A Combinatorial CRISPR–Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer TreatmentCombining Ifenprodil with Sorafenib for HCC Treatment F Xu, M Tong, CSW Tong, BKC Chan, HY Chu, TL Wong, JHC Fong, ... Cancer Research 81 (24), 6219-6232, 2021 | 10 | 2021 |
MQuad enables clonal substructure discovery using single cell mitochondrial variants AWC Kwok, C Qiao, R Huang, MH Sham, JWK Ho, Y Huang Nature Communications 13 (1), 1205, 2022 | 6 | 2022 |
Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy W Chen, JMN Teo, SW Yau, MYM Wong, CN Lok, CM Che, A Javed, ... Cell Reports 41 (7), 111647, 2022 | 5 | 2022 |
Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis Y Chao, Y Xiang, J Xiao, S Zhang, W Zheng, X Wan, Z Li, M Gao, G Wang, ... bioRxiv, 2022.09. 02.505700, 2022 | 3 | 2022 |
Uncertainty versus variability: Bayesian methods for analysis of scRNA-seq data Y Huang, G Sanguinetti Current Opinion in Systems Biology 28, 100375, 2021 | 3 | 2021 |
SpatialDM: Rapid identification of spatially co-expressed ligand-receptor reveals cell-cell communication patterns Z Li, T Wang, P Liu, Y Huang bioRxiv, 2022.08. 19.504616, 2022 | 2 | 2022 |
Using BRIE to detect and analyze splicing isoforms in scRNA-Seq data Y Huang, G Sanguinetti Computational Methods for Single-Cell Data Analysis, 175-185, 2019 | 2 | 2019 |