Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response CS Shi, GY Shi, HM Hsiao, YC Kao, KL Kuo, CY Ma, CH Kuo, BI Chang, ... Blood, The Journal of the American Society of Hematology 112 (9), 3661-3670, 2008 | 212 | 2008 |
Epstein–Barr Virus DNase (BGLF5) induces genomic instability in human epithelial cells CC Wu, MT Liu, YT Chang, CY Fang, SP Chou, HW Liao, KL Kuo, SL Hsu, ... Nucleic acids research 38 (6), 1932-1949, 2010 | 98 | 2010 |
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity SC Chao, YJ Chen, KH Huang, KL Kuo, TH Yang, KY Huang, CC Wang, ... Scientific reports 7 (1), 3180, 2017 | 93 | 2017 |
MLN4924, a novel protein neddylation inhibitor, suppresses proliferation and migration of human urothelial carcinoma: in vitro and in vivo studies KL Kuo, IL Ho, CS Shi, JT Wu, WC Lin, YC Tsai, HC Chang, CT Chou, ... Cancer letters 363 (2), 127-136, 2015 | 53 | 2015 |
MLN4924 synergistically enhances cisplatin-induced cytotoxicity via JNK and Bcl-xL pathways in human urothelial carcinoma IL Ho, KL Kuo, SH Liu, HC Chang, JT Hsieh, JT Wu, CK Chiang, WC Lin, ... Scientific reports 5 (1), 16948, 2015 | 45 | 2015 |
Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells KH Huang, KL Kuo, SC Chen, TI Weng, YT Chuang, YC Tsai, YS Pu, ... PLoS One 7 (3), e33615, 2012 | 44 | 2012 |
2-methoxyestradiol induces mitotic arrest, apoptosis, and synergistic cytotoxicity with arsenic trioxide in human urothelial carcinoma cells KL Kuo, WC Lin, IL Ho, HC Chang, PY Lee, YT Chung, JT Hsieh, YS Pu, ... PLoS One 8 (8), e68703, 2013 | 36 | 2013 |
The deubiquitinating enzyme inhibitor PR-619 enhances the cytotoxicity of cisplatin via the suppression of anti-apoptotic Bcl-2 protein: in vitro and in vivo study KL Kuo, SH Liu, WC Lin, PM Chow, YW Chang, SP Yang, CS Shi, CH Hsu, ... Cells 8 (10), 1268, 2019 | 25 | 2019 |
Trifluoperazine, an antipsychotic drug, effectively reduces drug resistance in cisplatin-resistant urothelial carcinoma cells via suppressing Bcl-xL: an in vitro and in vivo study KL Kuo, SH Liu, WC Lin, FS Hsu, PM Chow, YW Chang, SP Yang, CS Shi, ... International journal of molecular sciences 20 (13), 3218, 2019 | 23 | 2019 |
MLN4924, a Novel NEDD8-activating enzyme inhibitor, exhibits antitumor activity and enhances cisplatin-induced cytotoxicity in human cervical carcinoma: in vitro and in vivo study WC Lin, KL Kuo, CS Shi, JT Wu, JT Hsieh, HC Chang, SM Liao, CT Chou, ... American journal of cancer research 5 (11), 3350, 2015 | 23 | 2015 |
Celecoxib-induced cytotoxic effect is potentiated by inhibition of autophagy in human urothelial carcinoma cells KH Huang, KL Kuo, IL Ho, HC Chang, YT Chuang, WC Lin, PY Lee, ... PLoS One 8 (12), e82034, 2013 | 23 | 2013 |
The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma PM Chow, SH Liu, YW Chang, KL Kuo, WC Lin, KH Huang Cancer Letters 471, 27-37, 2020 | 20 | 2020 |
Histone deacetylase inhibitor, trichostatin A, synergistically enhances paclitaxel-induced cytotoxicity in urothelial carcinoma cells by suppressing the ERK pathway FS Hsu, JT Wu, JY Lin, SP Yang, KL Kuo, WC Lin, CS Shi, PM Chow, ... International Journal of Molecular Sciences 20 (5), 1162, 2019 | 19 | 2019 |
MLN4924, a protein neddylation inhibitor, suppresses the growth of human chondrosarcoma through inhibiting cell proliferation and inducing endoplasmic reticulum stress-related … MH Wu, CY Lee, TJ Huang, KY Huang, CH Tang, SH Liu, KL Kuo, ... International journal of molecular sciences 20 (1), 72, 2018 | 19 | 2018 |
Neddylation inhibitor, MLN4924 suppresses angiogenesis in huvecs and solid cancers: in vitro and in vivo study CS Shi, KL Kuo, WC Lin, MS Chen, SH Liu, SM Liao, CH Hsu, YW Chang, ... American journal of cancer research 10 (3), 953, 2020 | 17 | 2020 |
Suppression of angiogenesis by targeting cyclin-dependent kinase 7 in human umbilical vein endothelial cells and renal cell carcinoma: an in vitro and in vivo study CS Shi, KL Kuo, MS Chen, PM Chow, SH Liu, YW Chang, WC Lin, ... Cells 8 (11), 1469, 2019 | 12 | 2019 |
PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo … FS Hsu, WC Lin, KL Kuo, YL Chiu, CH Hsu, SM Liao, JR Dong, SH Liu, ... International journal of molecular sciences 22 (21), 11706, 2021 | 10 | 2021 |
Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma WC Lin, FS Hsu, KL Kuo, SH Liu, CT Shun, CS Shi, HC Chang, YC Tsai, ... Journal of Molecular Medicine 96, 1307-1318, 2018 | 9 | 2018 |
Epigallocatechin gallate attenuates partial bladder outlet obstruction-induced bladder injury via suppression of endoplasmic reticulum stress-related apoptosis—in vivo study JT Hsieh, KL Kuo, SH Liu, CS Shi, HC Chang, WC Lin, CT Chou, CH Hsu, ... Urology 91, 242. e1-242. e9, 2016 | 9 | 2016 |
CDK7 inhibition by THZ1 suppresses cancer stemness in both chemonaive and chemoresistant urothelial carcinoma via the hedgehog signaling pathway PM Chow, YW Chang, KL Kuo, WC Lin, SH Liu, KH Huang Cancer Letters 507, 70-79, 2021 | 7 | 2021 |