| The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling K Izutsu, M Kurokawa, Y Imai, K Maki, K Mitani, H Hirai Blood, The Journal of the American Society of Hematology 97 (9), 2815-2822, 2001 | 281 | 2001 |
| Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis Y Imai, M Kurokawa, K Izutsu, A Hangaishi, K Takeuchi, K Maki, S Ogawa, ... Blood, The Journal of the American Society of Hematology 96 (9), 3154-3160, 2000 | 202 | 2000 |
| The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability T Tanaka, M Kurokawa, K Ueki, K Tanaka, Y Imai, K Mitani, K Okazaki, ... Molecular and cellular biology, 1996 | 193 | 1996 |
| Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity K Kataoka, T Sato, A Yoshimi, S Goyama, T Tsuruta, H Kobayashi, ... Journal of Experimental Medicine 208 (12), 2403-2416, 2011 | 187 | 2011 |
| Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins A Yoshimi, S Goyama, N Watanabe-Okochi, Y Yoshiki, Y Nannya, E Nitta, ... Blood, The Journal of the American Society of Hematology 117 (13), 3617-3628, 2011 | 164 | 2011 |
| Influence of pretransplantation serum ferritin on nonrelapse mortality after myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantation K Kataoka, Y Nannya, A Hangaishi, Y Imai, S Chiba, T Takahashi, ... Biology of Blood and Marrow Transplantation 15 (2), 195-204, 2009 | 152 | 2009 |
| TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation Y Imai, M Kurokawa, K Tanaka, AD Friedman, S Ogawa, K Mitani, ... Biochemical and biophysical research communications 252 (3), 582-589, 1998 | 152 | 1998 |
| The t (3; 21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-β–mediated growth inhibition of myeloid cells M Kurokawa, K Mitani, Y Imai, S Ogawa, Y Yazaki, H Hirai Blood, The Journal of the American Society of Hematology 92 (11), 4003-4012, 1998 | 137 | 1998 |
| Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders K Ueda, Y Nannya, K Kumano, A Hangaishi, T Takahashi, Y Imai, ... International journal of hematology 89, 592-599, 2009 | 130 | 2009 |
| AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues Y Yamaguchi, M Kurokawa, Y Imai, K Izutsu, T Asai, M Ichikawa, ... Journal of Biological Chemistry 279 (15), 15630-15638, 2004 | 126 | 2004 |
| The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1 Y Imai, M Kurokawa, Y Yamaguchi, K Izutsu, E Nitta, K Mitani, M Satake, ... Molecular and cellular biology 24 (3), 1033-1043, 2004 | 123 | 2004 |
| Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes EJ Park, A Peixoto, Y Imai, A Goodarzi, G Cheng, CV Carman, ... Blood, The Journal of the American Society of Hematology 115 (8), 1572-1581, 2010 | 119 | 2010 |
| Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells S Arai, A Yoshimi, M Shimabe, M Ichikawa, M Nakagawa, Y Imai, ... Blood, The Journal of the American Society of Hematology 117 (23), 6304-6314, 2011 | 111 | 2011 |
| Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis Y Imai, M Kurokawa, K Izutsu, A Hangaishi, K Maki, S Ogawa, S Chiba, ... Oncogene 20 (1), 88-96, 2001 | 104 | 2001 |
| Notch1 oncoprotein antagonizes TGF‐β/Smad‐mediated cell growth suppression via sequestration of coactivator p300 S Masuda, K Kumano, K Shimizu, Y Imai, M Kurokawa, S Ogawa, ... Cancer science 96 (5), 274-282, 2005 | 90 | 2005 |
| The effect of iron overload and chelation on erythroid differentiation K Taoka, K Kumano, F Nakamura, M Hosoi, S Goyama, Y Imai, ... International journal of hematology 95, 149-159, 2012 | 84 | 2012 |
| EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization S Goyama, E Nitta, T Yoshino, S Kako, N Watanabe-Okochi, M Shimabe, ... Leukemia 24 (1), 81-88, 2010 | 78 | 2010 |
| Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells M Shimabe, S Goyama, N Watanabe-Okochi, A Yoshimi, M Ichikawa, ... Oncogene 28 (49), 4364-4374, 2009 | 77 | 2009 |
| Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies Y Imai, Y Maru, J Tanaka Cancer science 107 (11), 1543-1549, 2016 | 69 | 2016 |
| The AML1/ETO (MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2β (CBFβ) in the nucleus more efficiently than wild-type AML1 K Tanaka, T Tanaka, M Kurokawa, Y Imai, S Ogawa, K Mitani, Y Yazaki, ... Blood, The Journal of the American Society of Hematology 91 (5), 1688-1699, 1998 | 68 | 1998 |
