| CRISPR provides acquired resistance against viruses in prokaryotes R Barrangou, C Fremaux, H Deveau, M Richards, P Boyaval, S Moineau, ... Science 315 (5819), 1709-1712, 2007 | 7107 | 2007 |
| Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria G Gasiunas, R Barrangou, P Horvath, V Siksnys Proceedings of the National Academy of Sciences 109 (39), E2579-E2586, 2012 | 3445 | 2012 |
| Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011 | 3098 | 2011 |
| CRISPR/Cas, the immune system of bacteria and archaea P Horvath, R Barrangou Science 327 (5962), 167-170, 2010 | 3024 | 2010 |
| The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA JE Garneau, ME Dupuis, M Villion, DA Romero, R Barrangou, P Boyaval, ... Nature 468 (7320), 67-71, 2010 | 2975 | 2010 |
| An updated evolutionary classification of CRISPR-Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature Reviews Microbiology 13 (11), 722-736, 2015 | 2582 | 2015 |
| Phage response to CRISPR-encoded resistance in Streptococcus thermophilus H Deveau, R Barrangou, JE Garneau, J Labonté, C Fremaux, P Boyaval, ... Journal of bacteriology 190 (4), 1390-1400, 2008 | 1704 | 2008 |
| Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 1407 | 2020 |
| The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli R Sapranauskas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, ... Nucleic acids research 39 (21), 9275-9282, 2011 | 1388 | 2011 |
| Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus P Horvath, DA Romero, AC Coûté-Monvoisin, M Richards, H Deveau, ... Journal of bacteriology 190 (4), 1401-1412, 2008 | 1006 | 2008 |
| Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system T Sinkunas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, V Siksnys The EMBO journal 30 (7), 1335-1342, 2011 | 550 | 2011 |
| Bacterial stress responses G Storz, R Hengge American Society for Microbiology Press, 2010 | 521 | 2010 |
| Comparative analysis of CRISPR loci in lactic acid bacteria genomes P Horvath, AC Coûté-Monvoisin, DA Romero, P Boyaval, C Fremaux, ... International journal of food microbiology 131 (1), 62-70, 2009 | 347 | 2009 |
| crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus T Karvelis, G Gasiunas, A Miksys, R Barrangou, P Horvath, V Siksnys RNA biology 10 (5), 841-851, 2013 | 320 | 2013 |
| In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus T Sinkunas, G Gasiunas, SP Waghmare, MJ Dickman, R Barrangou, ... The EMBO journal 32 (3), 385-394, 2013 | 297 | 2013 |
| A decade of discovery: CRISPR functions and applications R Barrangou, P Horvath Nature microbiology 2 (7), 1-9, 2017 | 295 | 2017 |
| Programmable RNA Shredding by the Type III-A CRISPR-Cas System of Streptococcus thermophilus G Tamulaitis, M Kazlauskiene, E Manakova, Č Venclovas, AO Nwokeoji, ... Molecular cell 56 (4), 506-517, 2014 | 288 | 2014 |
| Use R Barrangou, P Boyaval, C Fremaux, P Horvath, D Romero US Patent App. 13/960,796, 2014 | 254 | 2014 |
| Use R Barrangou, P Boyaval, C Fremaux, P Horvath, D Romero US Patent App. 11/990,885, 2006 | 252* | 2006 |
| CRISPR: new horizons in phage resistance and strain identification R Barrangou, P Horvath Annual review of food science and technology 3, 143-162, 2012 | 251 | 2012 |
