| The cholinergic hypothesis of Alzheimer’s disease: a review of progress PT Francis, AM Palmer, M Snape, GK Wilcock Journal of Neurology, Neurosurgery & Psychiatry 66 (2), 137-147, 1999 | 2782 | 1999 |
| Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ... Archives of general psychiatry 67 (7), 739-748, 2010 | 466 | 2010 |
| Neurochemical studies of early-onset Alzheimer's disease: possible influence on treatment PT Francis, AM Palmer, NR Sims, DM Bowen, AN Davison, MM Esiri, ... New England Journal of Medicine 313 (1), 7-11, 1985 | 446 | 1985 |
| Cholinesterase inhibitors used in the treatment of Alzheimer’s disease: the relationship between pharmacological effects and clinical efficacy DG Wilkinson, PT Francis, E Schwam, J Payne-Parrish Drugs & aging 21, 453-478, 2004 | 423 | 2004 |
| Glutamatergic systems in Alzheimer's disease PT Francis International journal of geriatric psychiatry 18 (S1), S15-S21, 2003 | 341 | 2003 |
| Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future YE Geda, LS Schneider, LN Gitlin, DS Miller, GS Smith, J Bell, J Evans, ... Alzheimer's & dementia 9 (5), 602-608, 2013 | 328 | 2013 |
| Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives PT Francis, NR Sims, AW Procter, DM Bowen Journal of neurochemistry 60 (5), 1589-1604, 1993 | 318 | 1993 |
| The interplay of neurotransmitters in Alzheimer's disease PT Francis CNS spectrums 10 (S18), 6-9, 2005 | 317 | 2005 |
| Presynaptic serotonergic dysfunction in patients with Alzheimer's disease AM Palmer, PT Francis, JS Benton, NR Sims, DMA Mann, D Neary, ... Journal of neurochemistry 48 (1), 8-15, 1987 | 283 | 1987 |
| Cholinergic–serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer’s disease M Garcia-Alloza, FJ Gil-Bea, M Diez-Ariza, CPLH Chen, PT Francis, ... Neuropsychologia 43 (3), 442-449, 2005 | 260 | 2005 |
| Evidence of glutamatergic denervation and possible abnormal metabolism in Alzheimer's disease AW Procter, AM Palmer, PT Francis, SL Lowe, D Neary, E Murphy, ... Journal of neurochemistry 50 (3), 790-802, 1988 | 248 | 1988 |
| Metals ions and neurodegeneration F Molina-Holgado, RC Hider, A Gaeta, R Williams, P Francis Biometals 20, 639-654, 2007 | 245 | 2007 |
| Noradrenergic changes, aggressive behavior, and cognition in patients with dementia KL Matthews, CPLH Chen, MM Esiri, J Keene, SL Minger, PT Francis Biological psychiatry 51 (5), 407-416, 2002 | 234 | 2002 |
| Cholinergic deficits contribute to behavioral disturbance in patients with dementia SL Minger, MM Esiri, B McDonald, J Keene, J Carter, T Hope, PT Francis Neurology 55 (10), 1460-1467, 2000 | 229 | 2000 |
| AddNeuroMed—the European collaboration for the discovery of novel biomarkers for Alzheimer's disease S Lovestone, P Francis, I Kloszewska, P Mecocci, A Simmons, H Soininen, ... Annals of the New York Academy of Sciences 1180 (1), 36-46, 2009 | 225 | 2009 |
| Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease AM Palmer, GK Wilcock, MM Esiri, PT Francis, DM Bowen Brain research 401 (2), 231-238, 1987 | 221 | 1987 |
| Down‐regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease SL Kirvell, M Esiri, PT Francis Journal of neurochemistry 98 (3), 939-950, 2006 | 208 | 2006 |
| Apathy associated with neurocognitive disorders: recent progress and future directions KL Lanctôt, L Agüera-Ortiz, H Brodaty, PT Francis, YE Geda, Z Ismail, ... Alzheimer's & Dementia 13 (1), 84-100, 2017 | 204 | 2017 |
| Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of later life. DM Bowen, A Najlerahim, AW Procter, PT Francis, E Murphy Proceedings of the National Academy of Sciences 86 (23), 9504-9508, 1989 | 198 | 1989 |
| Regional multiple pathology scores are associated with cognitive decline in L ewy body dementias DR Howlett, D Whitfield, M Johnson, J Attems, JT O'Brien, D Aarsland, ... Brain pathology 25 (4), 401-408, 2015 | 187 | 2015 |
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