| Adapting proteostasis for disease intervention WE Balch, RI Morimoto, A Dillin, JW Kelly science 319 (5865), 916-919, 2008 | 2527 | 2008 |
| Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators RI Morimoto Genes & development 12 (24), 3788-3796, 1998 | 2324 | 1998 |
| Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome HM Beere, BB Wolf, K Cain, DD Mosser, A Mahboubi, T Kuwana, P Tailor, ... Nature cell biology 2 (8), 469-475, 2000 | 1910 | 2000 |
| Cells in stress: transcriptional activation of heat shock genes RI Morimoto Science 259 (5100), 1409-1410, 1993 | 1844 | 1993 |
| Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 1714 | 2014 |
| Heat shock factors: integrators of cell stress, development and lifespan M Åkerfelt, RI Morimoto, L Sistonen Nature reviews Molecular cell biology 11 (8), 545-555, 2010 | 1506 | 2010 |
| Role of the heat shock response and molecular chaperones in oncogenesis and cell death C Jolly, RI Morimoto Journal of the National Cancer Institute 92 (19), 1564-1572, 2000 | 1393 | 2000 |
| Biological and chemical approaches to diseases of proteostasis deficiency ET Powers, RI Morimoto, A Dillin, JW Kelly, WE Balch Annual review of biochemistry 78, 959-991, 2009 | 1349 | 2009 |
| The biology of heat shock proteins and molecular chaperones RI Morimoto, A Tissières | 1267* | 1994 |
| The biology of proteostasis in aging and disease J Labbadia, RI Morimoto Annual review of biochemistry 84, 435-464, 2015 | 1204 | 2015 |
| Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the … KD Sarge, SP Murphy, RI Morimoto Molecular and cellular biology 13 (3), 1392-1407, 1993 | 1113 | 1993 |
| Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. C Hunt, RI Morimoto Proceedings of the National Academy of Sciences 82 (19), 6455-6459, 1985 | 1099 | 1985 |
| Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging RI Morimoto Genes & development 22 (11), 1427-1438, 2008 | 1016 | 2008 |
| The chaperone function of hsp70 is required for protection against stress-induced apoptosis DD Mosser, AW Caron, L Bourget, AB Meriin, MY Sherman, RI Morimoto, ... Molecular and cellular biology 20 (19), 7146-7159, 2000 | 933 | 2000 |
| The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans JF Morley, HR Brignull, JJ Weyers, RI Morimoto Proceedings of the National Academy of Sciences 99 (16), 10417-10422, 2002 | 898 | 2002 |
| Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones JF Morley, RI Morimoto Molecular biology of the cell 15 (2), 657-664, 2004 | 849 | 2004 |
| Chaperoning signaling pathways: molecular chaperones as stress-sensingheat shock'proteins EAA Nollen, RI Morimoto Journal of cell science 115 (14), 2809-2816, 2002 | 842 | 2002 |
| Molecularchaperones as HSF1-specific transcriptional repressors Y Shi, DD Mosser, RI Morimoto Genes & development 12 (5), 654-666, 1998 | 801 | 1998 |
| Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development X Shen, RE Ellis, K Lee, CY Liu, K Yang, A Solomon, H Yoshida, ... Cell 107 (7), 893-903, 2001 | 787 | 2001 |
| Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1 SD Westerheide, J Anckar, SM Stevens Jr, L Sistonen, RI Morimoto Science 323 (5917), 1063-1066, 2009 | 782 | 2009 |
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