| Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong Nature 463 (7281), 689-692, 2010 | 670 | 2010 |
| Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ... Cell research 30 (8), 678-692, 2020 | 622 | 2020 |
| Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ... Science Advances 6 (50), eabe0751, 2020 | 266 | 2020 |
| Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus J Wang, Y Wu, C Ma, G Fiorin, J Wang, LH Pinto, RA Lamb, ML Klein, ... Proceedings of the National Academy of Sciences 110 (4), 1315-1320, 2013 | 235 | 2013 |
| Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are nonspecific promiscuous SARS-CoV-2 main protease inhibitors C Ma, Y Hu, JA Townsend, PI Lagarias, MT Marty, A Kolocouris, J Wang ACS pharmacology & translational science 3 (6), 1265-1277, 2020 | 166 | 2020 |
| Protein and small molecule microarrays: powerful tools for high-throughput proteomics M Uttamchandani, J Wang, SQ Yao Molecular Biosystems 2 (1), 58-68, 2006 | 153 | 2006 |
| Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19 B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ... Nature Communications 12 (1), 6055, 2021 | 148 | 2021 |
| Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2 J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, LH Pinto, ... Journal of the American Chemical Society 133 (32), 12834-12841, 2011 | 148 | 2011 |
| Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus J Wang, JX Qiu, C Soto, WF DeGrado Current opinion in structural biology 21 (1), 68-80, 2011 | 138 | 2011 |
| Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission NW Schmidt, A Mishra, J Wang, WF DeGrado, GCL Wong Journal of the American Chemical Society 135 (37), 13710-13719, 2013 | 135 | 2013 |
| The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor Y Hu, X Meng, F Zhang, Y Xiang, J Wang Emerging microbes & infections 10 (1), 317-330, 2021 | 123 | 2021 |
| Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus V Balannik, J Wang, Y Ohigashi, X Jing, E Magavern, RA Lamb, ... Biochemistry 48 (50), 11872-11882, 2009 | 118 | 2009 |
| Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine … SD Cady, J Wang, Y Wu, WF DeGrado, M Hong Journal of the American Chemical Society 133 (12), 4274-4284, 2011 | 114 | 2011 |
| Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ... Journal of medicinal chemistry 56 (7), 2804-2812, 2013 | 113 | 2013 |
| Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus J Wang, SD Cady, V Balannik, LH Pinto, WF DeGrado, M Hong Journal of the American Chemical Society 131 (23), 8066-8076, 2009 | 105 | 2009 |
| Discovery of a novel inhibitor of coronavirus 3CL protease for the potential treatment of COVID-19 B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ... BioRxiv, 2020.09. 12.293498, 2020 | 102 | 2020 |
| Proton and cation transport activity of the M2 proton channel from influenza A virus T Leiding, J Wang, J Martinsson, WF DeGrado, SP Årsköld Proceedings of the National Academy of Sciences 107 (35), 15409-15414, 2010 | 97 | 2010 |
| Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters JL Thomaston, NF Polizzi, A Konstantinidi, J Wang, A Kolocouris, ... Journal of the American Chemical Society 140 (45), 15219-15226, 2018 | 91 | 2018 |
| Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 … Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ... Journal of the American Chemical Society 136 (52), 17987-17995, 2014 | 84 | 2014 |
| Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus MD Duque, C Ma, E Torres, J Wang, L Naesens, J Juárez-Jiménez, ... Journal of medicinal chemistry 54 (8), 2646-2657, 2011 | 80 | 2011 |
Chunlong MaResearch specialist在 pharmacy.arizona.edu 的电子邮件经过验证
