Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo J Chen, PR Somanath, O Razorenova, WS Chen, N Hay, P Bornstein, ... Nature medicine 11 (11), 1188-1196, 2005 | 510 | 2005 |
Akt1 in endothelial cell and angiogenesis PR Somanath, OV Razorenova, J Chen, TV Byzova Cell cycle 5 (5), 512-518, 2006 | 325 | 2006 |
Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis PR Somanath, NL Malinin, TV Byzova Angiogenesis 12, 177-185, 2009 | 307 | 2009 |
Antiangiogenic therapy for cancer: an update B Al‐Husein, M Abdalla, M Trepte, DL DeRemer, PR Somanath Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 32 (12 …, 2012 | 241 | 2012 |
Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression ST Kochuparambil, B Al-Husein, A Goc, S Soliman, PR Somanath Journal of Pharmacology and Experimental Therapeutics 336 (2), 496-505, 2011 | 160 | 2011 |
Integrin and growth factor receptor alliance in angiogenesis PR Somanath, A Ciocea, TV Byzova Cell biochemistry and biophysics 53, 53-64, 2009 | 146 | 2009 |
Novel roles of Src in cancer cell epithelial-to-mesenchymal transition, vascular permeability, microinvasion and metastasis A Patel, H Sabbineni, A Clarke, PR Somanath Life sciences 157, 52-61, 2016 | 145 | 2016 |
Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly PR Somanath, ES Kandel, N Hay, TV Byzova Journal of Biological Chemistry 282 (31), 22964-22976, 2007 | 137 | 2007 |
PAK1 as a therapeutic target JV Kichina, A Goc, B Al-Husein, PR Somanath, ES Kandel Expert opinion on therapeutic targets 14 (7), 703-725, 2010 | 131 | 2010 |
Enhanced cerebral but not peripheral angiogenesis in the Goto-Kakizaki model of type 2 diabetes involves VEGF and peroxynitrite signaling R Prakash, PR Somanath, AB El-Remessy, A Kelly-Cobbs, JE Stern, ... Diabetes 61 (6), 1533-1542, 2012 | 110 | 2012 |
Regulation of blood-retinal barrier cell-junctions in diabetic retinopathy M Rudraraju, SP Narayanan, PR Somanath Pharmacological research 161, 105115, 2020 | 107 | 2020 |
P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 … A Goc, A Al-Azayzih, M Abdalla, B Al-Husein, S Kavuri, J Lee, K Moses, ... Journal of Biological Chemistry 288 (5), 3025-3035, 2013 | 99 | 2013 |
Integrin affinity modulation in angiogenesis GH Mahabeleshwar, J Chen, W Feng, PR Somanath, OV Razorenova, ... Cell Cycle 7 (3), 335-347, 2008 | 99 | 2008 |
Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment JW Ye, JX Cai, LM Wang, XC Tang Journal of Pharmacology and Experimental Therapeutics 288 (2), 814-819, 1999 | 96 | 1999 |
Changes in sperm glycogen synthase kinase‐3 serine phosphorylation and activity accompany motility initiation and stimulation PR Somanath, SL Jack, S Vijayaraghavan Journal of andrology 25 (4), 605-617, 2004 | 94 | 2004 |
Diverse effects of statins on angiogenesis: new therapeutic avenues HF Elewa, AB El‐Remessy, PR Somanath, SC Fagan Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 30 (2 …, 2010 | 86 | 2010 |
Akt1 is necessary for the vascular maturation and angiogenesis during cutaneous wound healing PR Somanath, J Chen, TV Byzova Angiogenesis 11, 277-288, 2008 | 85 | 2008 |
Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis A Goc, ST Kochuparambil, B Al-Husein, A Al-Azayzih, S Mohammad, ... BMC cancer 12, 1-13, 2012 | 84 | 2012 |
Deficiency in core circadian protein Bmal1 is associated with a prothrombotic and vascular phenotype PR Somanath, EA Podrez, J Chen, YI Ma, K Marchant, M Antoch, ... Journal of cellular physiology 226 (1), 132-140, 2011 | 80 | 2011 |
Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo A Goc, B Al-Husein, K Katsanevas, A Steinbach, U Lou, H Sabbineni, ... Oncotarget 5 (3), 775, 2014 | 77 | 2014 |