Glucosylation and ADP ribosylation of rho proteins: effects on nucleotide binding, GTPase activity, and effector coupling P Sehr, G Joseph, H Genth, I Just, E Pick, K Aktories Biochemistry 37 (15), 5296-5304, 1998 | 262 | 1998 |
Sphingosine-1-phosphate mediates migration of mature dendritic cells N Czeloth, G Bernhardt, F Hofmann, H Genth, R Förster The Journal of Immunology 175 (5), 2960-2967, 2005 | 240 | 2005 |
Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni M Krause‐Gruszczynska, M Rohde, R Hartig, H Genth, G Schmidt, T Keo, ... Cellular microbiology 9 (10), 2431-2444, 2007 | 150 | 2007 |
Clostridium difficile toxins: more than mere inhibitors of Rho proteins H Genth, SC Dreger, J Huelsenbeck, I Just The international journal of biochemistry & cell biology 40 (4), 592-597, 2008 | 145 | 2008 |
Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling J Kamanova, O Kofronova, J Masin, H Genth, J Vojtova, I Linhartova, ... The journal of immunology 181 (8), 5587-5597, 2008 | 132 | 2008 |
Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC S Conrad, H Genth, F Hofmann, I Just, T Skutella Journal of biological chemistry 282 (22), 16423-16433, 2007 | 127 | 2007 |
Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling H Genth, K Aktories, I Just Journal of biological chemistry 274 (41), 29050-29056, 1999 | 126 | 1999 |
Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex H Genth, R Gerhard, A Maeda, M Amano, K Kaibuchi, K Aktories, I Just Journal of Biological Chemistry 278 (31), 28523-28527, 2003 | 120 | 2003 |
Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling S Busche, A Descot, S Julien, H Genth, G Posern Journal of cell science 121 (7), 1025-1035, 2008 | 108 | 2008 |
Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B H Genth, J Huelsenbeck, B Hartmann, F Hofmann, I Just, R Gerhard FEBS letters 580 (14), 3565-3569, 2006 | 99 | 2006 |
Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling O Pochynyuk, J Medina, N Gamper, H Genth, JD Stockand, ... Journal of Biological Chemistry 281 (36), 26520-26527, 2006 | 95 | 2006 |
Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system S Burger, H Tatge, F Hofmann, H Genth, I Just, R Gerhard Biochemical and biophysical research communications 307 (3), 584-588, 2003 | 87 | 2003 |
Recognition of RhoA by Clostridium botulinum C3 exoenzyme C Wilde, H Genth, K Aktories, I Just Journal of Biological Chemistry 275 (22), 16478-16483, 2000 | 87 | 2000 |
Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB R Gerhard, H Tatge, H Genth, T Thum, J Borlak, G Fritz, I Just Journal of Biological Chemistry 280 (2), 1499-1505, 2005 | 81 | 2005 |
The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNFY) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases J Schweer, D Kulkarni, A Kochut, J Pezoldt, F Pisano, MC Pils, H Genth, ... PLoS pathogens 9 (11), e1003746, 2013 | 80 | 2013 |
Difference in the Cytotoxic Effects of Toxin B from Clostridium difficile Strain VPI 10463 and Toxin B from Variant Clostridium difficile Strain 1470 J Huelsenbeck, S Dreger, R Gerhard, H Barth, I Just, H Genth Infection and immunity 75 (2), 801-809, 2007 | 80 | 2007 |
Difference in protein substrate specificity between hemorrhagic toxin and lethal toxin fromClostridium sordellii H Genth, F Hofmann, J Selzer, G Rex, K Aktories, I Just Biochemical and biophysical research communications 229 (2), 370-374, 1996 | 80 | 1996 |
Actin re-organization induced by Chlamydia trachomatis serovar D-evidence for a critical role of the effector protein CT166 targeting Rac J Thalmann, K Janik, M May, K Sommer, J Ebeling, F Hofmann, H Genth, ... PLoS One 5 (3), e9887, 2010 | 71 | 2010 |
Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK … X Tan, A Xu, T Zhao, Q Zhao, J Zhang, C Fan, Y Deng, A Freywald, ... Scientific reports 8 (1), 3769, 2018 | 68 | 2018 |
Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases S Nottrott, J Schoentaube, H Genth, I Just, R Gerhard Apoptosis 12, 1443-1453, 2007 | 67 | 2007 |