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Introduction. Health Observatories have gained global popularity and have been established worldwide since the 1970s. With the advent of the Semantic Web, machines can process, reuse, integrate and understand the meaning (semantics) of the information and knowledge on the World Wide Web to perform complex tasks. Objective. To propose a health observatory conceptual model based on Semantic Web in order to assist in the design, development and implementation processes of a Health Observatory. Methods. The proposed model was based on a conceptual analysis that include Semantic Web technologies narrative review, multi-layer software architecture and an integrative review of Health Observatories. Results. The proposed Health Observatory conceptual model consists of a chain of several related components based on information technology multi-layer architecture, Semantic Web technologies …