作者
Kristen A Hahn, Elizabeth E Hatch, Kenneth J Rothman, Ellen M Mikkelsen, Susan B Brogly, Henrik T Sørensen, Anders H Riis, Lauren A Wise
发表日期
2014/9
期刊
Paediatric and perinatal epidemiology
卷号
28
期号
5
页码范围
412-423
简介
Background
Several studies indicate that female obesity increases the risk of spontaneous abortion (SAB). Central adiposity, height, and location of typical weight gain have not been examined as risk factors for SAB.
Methods
We examined the associations between selected anthropometric factors and risk of SAB among 5132 women enrolled in a Danish Internet‐based prospective cohort study of pregnancy planners. We used Cox proportional hazards regression models, with gestational weeks as the time scale, to compute hazard ratios (HRs) of SAB and 95% confidence intervals (CIs).
Results
After adjustment for potential confounders, the HRs for SAB among underweight (body mass index (BMI, kg/m2) <20), overweight (BMI: 25–29) and obese (BMI ≥30) women were 1.00 [95% CI: 0.81, 1.24], 0.90 [95% CI: 0.73, 1.09] and 1.23 [95% CI: 0.98, 1.54], respectively, compared with normal weight women (BMI 20 …
引用总数
2015201620172018201920202021202220232024193716466102
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KA Hahn, EE Hatch, KJ Rothman, EM Mikkelsen… - Paediatric and perinatal epidemiology, 2014