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Because the optimal concentration of oxygen (FiO₂) required for stabilization of the newly born infant has not been established, the FiO₂ is commonly adjusted according to the infant’s oxygen saturation (SpO₂). We aimed to determine the range of pre-ductal SpO₂ in the first minutes of life in healthy newborn infants.

We applied an oximetry sensor to the infant’s right palm or wrist of term and preterm deliveries immediately after birth. Infants who received any resuscitation or supplemental oxygen were excluded. SpO₂ was recorded at 60 second intervals for at least 5 minutes and until the SpO₂ was >90%.

A total of 205 deliveries were monitored; 30 infants were excluded from the study. SpO₂ readings were obtained within 60 seconds of age from 92 of 175 infants (53%). The median (interquartile range) SpO₂ at 1 minute was 63% (53%-68%). There was a gradual rise in …