作者
Kingsley Dah, Mateo Porres-Aguilar, Alan De la Rosa, Swathi Prakash
发表日期
2023/6/30
期刊
Jornal Vascular Brasileiro
卷号
22
页码范围
e20230056
出版商
Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
简介
Direct oral anticoagulants (DOACs) have become the standard of care for acute and long-term therapy for venous thromboembolism (VTE) due to their efficacy and safety profiles. The 2021 International Society on Thrombosis and Haemostasis guidelines recommend using standard DOAC dosages in patients with BMI >40 kg/m2 or weight >120 kg. Use of DOACs remains uncertain in morbidly obese patients with VTE, including acute PE. A morbidly obese woman in her 30s who presented with acute worsening of dyspnea was diagnosed with acute intermediate-high risk acute pulmonary embolism and concomitant proximal deep vein thrombosis, constituting a clinically challenging scenario for treating her with rivaroxaban. Standard doses of rivaroxaban for acute and extended phase treatment of venous thromboembolism in individuals with morbid obesity at BMI>70 kg/m2 may be effective, and safe.
学术搜索中的文章
K Dah, M Porres-Aguilar, AD Rosa, S Prakash - Jornal Vascular Brasileiro, 2023