作者
B Howley, HO Fearnhead
发表日期
2008/9
来源
Journal of cellular and molecular medicine
卷号
12
期号
5a
页码范围
1502-1516
出版商
Blackwell Publishing Ltd
简介
- • Introduction
- • Activation of caspases
- ‐ Activation of apoptotic caspases
- ‐ Activation of inflammatory caspases
- ‐ Interleukins, their activation by caspases and their role in inflammation
- ‐
- • Small molecule inhibitors of caspase activity and activation
- ‐ Modification of caspase activation
- ‐ Synthetic molecules as inhibitors of caspase activity
- ‐
- • Role of caspases in disease
- ‐ Caspases as targets in conditions associated with increased levels of apoptosis
- ‐ Neurodegenerative disease
- ‐ Ischaemia
- ‐ Ischaemia/reperfusion injury – implications in transplant injury
- ‐ Inflammatory diseases
- ‐ Role of caspases in sepsis – mediators of apoptosis and inflammation
- ‐ Role of caspase‐1 and ‐12 in sepsis
- ‐ Role of apoptotic caspases in sepsis
- ‐
- • Challenges facing the development of caspase therapeutics
- • Role of caspases in other aspects of cell death
- • Role of caspases in non …
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B Howley, HO Fearnhead - Journal of cellular and molecular medicine, 2008