作者
Jennifer Yee-Man Tang, Wing-Chung Chang, Christy Lai-Ming Hui, Gloria Hoi-Yan Wong, Sherry Kit-Wa Chan, Edwin Ho-Ming Lee, Wai-Song Yeung, Chi-Keung Wong, Wai-Nang Tang, Wah-Fat Chan, Edwin Pui-Fai Pang, Steve Tso, Roger Man-Kin Ng, Se-Fong Hung, Eva Lai-Wah Dunn, Pak-Chung Sham, Eric Yu-Hai Chen
发表日期
2014/3/1
期刊
Schizophrenia research
卷号
153
期号
1-3
页码范围
1-8
出版商
Elsevier
简介
Background
The adverse effects of a long duration of untreated psychosis (DUP) have been explored in numerous short-term studies. These studies support the development of early interventions that reduce treatment delay and promote recovery. However, the enduring impact of DUP is largely unknown, partly due to the paucity of prospective long-term studies. Although the DUP–outcome relationship is commonly assumed to be linear, the threshold effect has not been adequately examined.
Objective
To explore the relationship between DUP and long-term symptomatic remission.
Methods
This was a prospective study of a cohort of 153 first-episode psychosis patients in Hong Kong at the 13-year follow-up. The patients were categorized into short (≤ 30 days), medium (31–180 days) and long (> 180 days) DUP groups.
Results
The long-term outcome was ascertained in 73% of the patients. Nearly half of the patients …
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JYM Tang, WC Chang, CLM Hui, GHY Wong… - Schizophrenia research, 2014