作者
Erika Rubesova, Anne‐Sophie Grell, Viviane De Maertelaer, Thierry Metens, Shih‐Li Chao, Marc Lemort
发表日期
2006/8
期刊
Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine
卷号
24
期号
2
页码范围
319-324
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Purpose
To study the correlation between apparent diffusion coefficient (ADC) and pathology in patients with undefined breast lesion, to validate how accurately ADC is related to histology, and to define a threshold value of ADC to distinguish malignant from benign lesions.
Materials and Methods
Seventy‐eight patients (110 lesions) were referred for positive or dubious findings. Three‐dimensional fast low‐angle shot (3D‐FLASH) with contrast injection was applied. EPI diffusion‐weighted imaging (DWI) with fat saturation was performed, and ROIs were selected on subtraction 3D‐FLASH images before and after contrast injection, and copied on an ADC map. Inter‐ and intraobserver analyses were performed.
Results
At pathology 22 lesions were benign, 65 were malignant, and 23 were excluded. The ADCs of malignant and benign lesions were statistically different. In malignant tumors the ADC was (mean ± …
引用总数
学术搜索中的文章
E Rubesova, AS Grell, V De Maertelaer, T Metens… - Journal of Magnetic Resonance Imaging: An Official …, 2006