… of low dose amitriptyline users (< 25 mg amitriptyline), but this … of subjects while cost-effectiveness
is a consideration of increas… during treatment with antidepressants-a pilot study. Clin …

… the translation of genotype to phenotype for CYP2D6 is often performed … , amitriptyline and
nortriptyline also undergo CYP2D6 … , studies have demonstrated a probable reduced efficacy …

… poor preventing effect of metabolic control in type 2 diabetes (… antidepressants such as
amitriptyline acting as blocker of … patient with painful diabetic peripheral neuropathy having a …

… l/l genotype are immune to the depressogenic effects of early … One small pilot study of
childhood depression (ages 6–12) … Other paths of metabolism include hydroxylation by CYP2D6 …

… Mutations in either of these 2 genes affect the efficacy of … for side effects of amitriptyline
therapy. Carriers of 2 functional … A recent pilot study suggests that genetic variations in the …

… some tricyclic antidepressants like amitriptyline, imipramine and … In a German study evaluating
the effect of CYP2D6 genotype … which could affect safety and efficacy of the treatment with …

… /CYP, safety, efficacy/effect, adverse effects/adverse reactions … amitriptyline is widely used
for the prophylactic treatment of … the treatment responses to valproic acid and MDR1, CYP2D6, …

… In a study of experimental pain in volunteers genotyped for … and subcutaneous lidocaine
efficacy have been attributed in … of CYP2D6 might benefit from treatment with antiemetics that …

… (s) for maximum effectiveness, while minimizing side effects (SE) and … yet the TCA amitriptyline
is influenced by both CYP2D6 and … : CYP2D6 genotyping for safe and efficacious codeine …

… and CYP2D6 have been associated with its efficacy and the risk for side effects in amitriptyline
therapy… and disease outcome in osteosarcoma: A pilot study. Cancer 2012; 118: 1856–67. …