… In this scenario, viral protease enzymes are crucial targets for drug discovery. This … focused
on two viral proteases such as main protease (Mpro) and papain-like protease (PLpro), those …

… The present study focused on the main proteases in CoVs (3CLpro/Mpro), especially PDB
ID 6LU7, as potential target proteins for COVID-19 treatment. 6LU7 is the Mpro in COVID-19 …

… This might explain why statins could be useful in the treatment of COVID-19. … COVID-19
Mpro inhibitors. Namely, most recently the SARS-CoV-2 main protease (Mpro), a key coronavirus …

… coronavirus-caused infectious diseases, including COVID-19. This … syndrome coronavirus
2 (SARS-CoV-2) main protease M pro … as novel anti-coronavirus therapies are also proposed. …

… antivirals specific to COVID-19 treatment. The 2019-nCoV and SARS-CoV utilize the same
receptor of the host which is COVID-19 of the main protease (Mpro).COVID-19 caused by …

… The α-ketoamide inhibitor 13b showed an IC 50 value of 0.67 μM for purified recombinant
SARS-CoV-2 main protease 3CL pro and also showed inhibitory activity against COVID-19 …

… Coronavirus disease-2019 (COVID-19) virus has emerged in Wuhan, China. In this research,
the first resolved COVID-19 crystal structure (main protease) … relations of COVID-19 with the …

… An attractive drug target among coronaviruses is the main protease (M pro , 3CL pro ), due …
focused on the main proteases in CoVs as potential target proteins for COVID-19 treatment. M …

… studies against the recent coronavirus epidemics, including … described for the treatment of
COVID-19 (Azithromycin, Baricitinib… ) compared to the COVID-19 main protease in the complex …

… Possible docking modes between compounds and the main protease of COVID-19 were
studied using the Molegro Virtual Docker 7 (15). The score function used is MolDock score with …