Potential of plant extracts in targeting SARS-CoV-2 main protease: an in vitro and in silico study
IG de Araujo, JR Pattaro-Junior… - Journal of …, 2023 - Taylor & Francis
The deaths caused by the covid-19 pandemic have recently decreased due to a worldwide
effort in vaccination campaigns. However, even vaccinated people can develop a severe …
effort in vaccination campaigns. However, even vaccinated people can develop a severe …
The inhibitory effect of some natural bioactive compounds against SARS-CoV-2 main protease: insights from molecular docking analysis and molecular dynamic …
DA Abdelrheem, SA Ahmed… - … Science and Health …, 2020 - Taylor & Francis
This work aimed at evaluating the inhibitory effect of ten natural bioactive compounds (1–10)
as potential inhibitors of SARS-CoV-2-3CL main protease (PDB ID: 6LU7) and SARS-CoV …
as potential inhibitors of SARS-CoV-2-3CL main protease (PDB ID: 6LU7) and SARS-CoV …
Repurposing of FDA approved drugs for the identification of potential inhibitors of SARS-CoV-2 main protease
COVID-19, responsible for several deaths, demands a cumulative effort of scientists
worldwide to curb the pandemic. The main protease, responsible for the cleavage of the …
worldwide to curb the pandemic. The main protease, responsible for the cleavage of the …
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
FA Ambrosio, G Costa, I Romeo… - Journal of Chemical …, 2023 - ACS Publications
The SARS-CoV-2 main protease (Mpro) is a crucial enzyme for viral replication and has
been considered an attractive drug target for the treatment of COVID-19. In this study, virtual …
been considered an attractive drug target for the treatment of COVID-19. In this study, virtual …
Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PLPRO and 3CLPRO proteases
Abstract The pandemic, COVID-19, has spread worldwide and affected millions of people.
There is an urgent need, therefore, to find a proper treatment for the novel coronavirus …
There is an urgent need, therefore, to find a proper treatment for the novel coronavirus …
A dynamic simulation study of FDA drug from zinc database against COVID-19 main protease receptor
The sudden outbreak of COVID-19 has been responsible for several deaths across the
globe. Due to its high contagious nature, it spreads from one human to another very quickly …
globe. Due to its high contagious nature, it spreads from one human to another very quickly …
In silico identification of potent FDA approved drugs against Coronavirus COVID-19 main protease: A drug repurposing approach
Abstract The Coronavirus COVID-19 Main Proteases play critical role in the propagation of
the Novel Coronavirus (COVID-19). We have applied a bioinformatics approach of drug …
the Novel Coronavirus (COVID-19). We have applied a bioinformatics approach of drug …
In silico prediction of novel inhibitors of SARS-CoV-2 main protease through structure-based virtual screening and molecular dynamic simulation
The unprecedented pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is threatening global health. SARS-CoV-2 has caused severe disease with …
CoV-2) is threatening global health. SARS-CoV-2 has caused severe disease with …
Identification of potential inhibitors of three key enzymes of SARS-CoV2 using computational approach
H Iftikhar, HN Ali, S Farooq, H Naveed… - Computers in biology …, 2020 - Elsevier
The recent outbreak of coronavirus disease-19 (COVID-19) continues to drastically affect
healthcare throughout the world. To date, no approved treatment regimen or vaccine is …
healthcare throughout the world. To date, no approved treatment regimen or vaccine is …
[HTML][HTML] Computer-aided design, syntheses, and ITC binding data of novel flavanone derivatives for use as potential inhibitors of the papain-like protease of COVID-19
AJ Sigmon, E Margulis, C George, TN Laremore… - Results in …, 2023 - Elsevier
The papain-like protease (PL pro) of SARS-CoV-2 (COVID-19) is a high-profile drug target
for treating COVID-19 due to its critical role in making essential proteins crucial in viral …
for treating COVID-19 due to its critical role in making essential proteins crucial in viral …