Inflammasome is a very important signaling platform sensing a variety of triggers of the
innate immune system. Inflammasome promotes the production of important pro …

Inflammasomes are key inflammatory signaling platforms that detect microbial substances,
sterile environmental insults, and molecules derived from host cells. Activation of the …

Inflammasomes are a group of protein complex located in cytoplasm and assemble in
response to a wide variety of pathogen‐associated molecule patterns, damage‐associated …

In modern vaccines, adjuvants can be sophisticated immunological tools to promote robust
and long-lasting protection against prevalent diseases. However, there is an urgent need to …

As key regulators of both innate and adaptive immunity, it is unsurprising that the activity of
interleukin (IL)-1 cytokine family members is tightly controlled by decoy receptors …

Inflammasomes are large cytosolic multiprotein complexes assembled in response to
infection and cellular stress, and are crucial for the activation of inflammatory caspases and …

A complex interplay between pathogen and host determines the immune response during
viral infection. A set of cytosolic sensors are expressed by immune cells to detect viral …

Inflammasomes are key signalling platforms that detect pathogenic microorganisms and
sterile stressors, and that activate the highly pro-inflammatory cytokines interleukin-1β (IL …

Summary Interleukin‐1β (IL‐1β) is a potent inflammatory cytokine, which is implicated in
acute and chronic inflammatory disorders. The activity of IL‐1β is regulated by the proteolytic …

Inflammasome molecules make up a family of receptors that typically function to initiate a
proinflammatory response upon infection by microbial pathogens. Dysregulation of …