This review sought to assess the efficacy, effectiveness and safety of high‐dose inactivated
influenza vaccines (HD‐IIV) for the prevention of laboratory‐confirmed influenza in …

Background: Influenza is responsible for a significant disease burden annually, especially in
older adults. This study reviews the relative vaccine efficacy or effectiveness (rVE) of high …

Objectives Summary evidence of influenza vaccine effectiveness (IVE) against hospitalized
influenza is lacking. We conducted a meta-analysis of studies reporting IVE against …

This updated systematic review and meta-analysis of randomized and observational studies
published up to April 2023 assessed the relative performance of high-dose inactivated …

Background Influenza vaccine efficacy/effectiveness can vary from season to season due in
part to the dominant circulating strains and antigenic matching. This study reviews the …

Background As compared with a standard-dose vaccine, a high-dose, trivalent, inactivated
influenza vaccine (IIV3-HD) improves antibody responses to influenza among adults 65 …

The most effective means of preventing seasonal influenza is through vaccination. In this
systematic review, we investigated the efficacy, effectiveness and safety of MF59® …

Background A recent study showed that a high-dose inactivated influenza vaccine (IIV-HD)
was 24.2% more efficacious than a standard-dose inactivated influenza vaccine (IIV-SD) in …

Influenza is a respiratory disease caused by the influenza virus, which is highly
transmissible in humans. This paper presents a systematic review and meta-analysis of …

Introduction Older adults are prioritized for influenza vaccination but also have lowered
antibody responses to the vaccine. Higher-doses of influenza antigen may increase immune …