The development of inhibitors that target the papain‐like protease (PLpro) has the potential
to counteract the spread of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV …

The global impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
companion disease, COVID-19, has reminded us of the importance of basic coronaviral …

The pandemic caused by SARS-CoV-2 (SCoV-2) has impacted the world in many ways and
the virus continues to evolve and produce novel variants with the ability to cause frequent …

Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with very limited treatments so far …

The emergent outbreak caused by severe acute respiratory syndrome coronavirus 2
continues spreading and causing huge social and economic disruption. Papain-like …

ABSTRACT SARS-CoV-2 PLpro was investigated as a therapeutic target for potent antiviral
drugs due to its essential role in not only viral replication but also in regulating the inborn …

The papain-like protease (PLpro) from zoonotic coronaviruses (CoVs) has been identified as
a target with an essential role in viral respiratory diseases caused by Severe Acute …

The highly infectious respiratory illness 'COVID-19'was caused by SARS-CoV-2 and is
responsible for millions of deaths. SARS-single-stranded viral RNA genome encodes …

The papain-like protease (PL pro) is vital for the replication of coronaviruses (CoVs), as well
as for escaping innate-immune responses of the host. Hence, it has emerged as an …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses a
multifunctional papain-like proteinase (PLpro), which mediates the processing of the viral …