Advanced nanoscale delivery systems for mRNA-based vaccines
The effectiveness of messenger RNA (mRNA) vaccines, especially those designed for
COVID-19, relies heavily on sophisticated delivery systems that ensure efficient delivery of …
COVID-19, relies heavily on sophisticated delivery systems that ensure efficient delivery of …
Recent advances in the lipid nanoparticle-mediated delivery of mRNA vaccines
Lipid nanoparticles (LNPs) have recently emerged as one of the most advanced
technologies for the highly efficient in vivo delivery of exogenous mRNA, particularly for …
technologies for the highly efficient in vivo delivery of exogenous mRNA, particularly for …
Emerging advances in delivery systems for mRNA cancer vaccines
Z Jiang, Y Xu, G Du, X Sun - Journal of Controlled Release, 2024 - Elsevier
The success of lipid nanoparticles (LNPs) in treating COVID-19 promotes further research of
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …
Nanomaterial delivery systems for mRNA vaccines
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …
development of lipid nanoparticle delivery systems that not only efficiently express the …
Lipid nanoparticles as delivery systems for RNA-based vaccines
BN Aldosari, IM Alfagih, AS Almurshedi - Pharmaceutics, 2021 - mdpi.com
There has been increased interest in the development of RNA-based vaccines for protection
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …
Opportunities for innovation: Building on the success of lipid nanoparticle vaccines
J Huang, D Yuen, JD Mintern, APR Johnston - Current opinion in colloid & …, 2021 - Elsevier
Lipid nanoparticle (LNP) formulations of messenger RNA (mRNA) have demonstrated high
efficacy as vaccines against SARS-CoV-2. The success of these nanoformulations …
efficacy as vaccines against SARS-CoV-2. The success of these nanoformulations …
Lipid Nanoparticle-Based Delivery System─ A Competing Place for mRNA Vaccines
X Zhang, Y Li, Z Zhou - ACS omega, 2024 - ACS Publications
mRNA, as one of the foci of biomedical research in the past decade, has become a
candidate vaccine solution for various infectious diseases and tumors and for regenerative …
candidate vaccine solution for various infectious diseases and tumors and for regenerative …
Material design for next-generation mrna vaccines using lipid nanoparticles
Vaccine development is among the critical issues for ceasing the COVID-19 pandemic. This
review discusses the current usage of biomaterials in vaccine development and provides …
review discusses the current usage of biomaterials in vaccine development and provides …
Lipid nanoparticle delivery systems to enable mRNA-based therapeutics
SC Semple, R Leone, CJ Barbosa, YK Tam, PJC Lin - Pharmaceutics, 2022 - mdpi.com
The world raced to develop vaccines to protect against the rapid spread of SARS-CoV-2
infection upon the recognition of COVID-19 as a global pandemic. A broad spectrum of …
infection upon the recognition of COVID-19 as a global pandemic. A broad spectrum of …
Lipid-based delivery systems in development of genetic and subunit vaccines
A Bolhassani - Molecular Biotechnology, 2023 - Springer
Lipidic carriers are composed of natural, synthetic, or physiological lipid/phospholipid
materials. The flexibility of lipid-based delivery systems for transferring a variety of molecules …
materials. The flexibility of lipid-based delivery systems for transferring a variety of molecules …