A structured development approach is presented to guide the development of stable and
commercially viable polymer based amorphous formulations. The proposed approach …

A structured development approach is presented to guide the development of stable and
commercially viable amorphous formulations. The proposed approach should not only …

Amorphous solid dispersion (ASD) can accelerate a project by improving dissolution rate
and solubility, offering dose escalation flexibility and excipient acceptance for toxicology …

Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

The present work highlights the use of miniaturized approaches to screen and prioritize
development of solid dispersions that provide stabilization of the amorphous drug against …

Evolving therapeutic landscape through combinatorial chemistry and high throughput
screening have resulted in an increased number of poorly soluble drugs. Drug delivery …

Amorphous Solid Dispersions (ASDs) have indeed revolutionized the pharmaceutical
industry, particularly in drug solubility enhancement. The amorphous state of a drug, which …

Amorphous solid dispersions stabilized by one or more polymer (s) have been widely used
for delivering amorphous drugs with poor water solubilities, and they have gained great …

Providing a roadmap from early to late stages of drug development, this book overviews
amorphous solid dispersion technology–a leading platform to deliver poorly water soluble …

Introduction: Poor aqueous solubility of active pharmaceutical ingredients (APIs) is one of
the main challenges in the development of new small molecular drugs. Additionally, the …