Three cohort studies in adults were performed during the periode from 1986 to 1989. Eight
hundred and eighty-four subjects were, one or more times, immunized with influenza …

Objective.—To determine the efficacy of influenza vaccination in elderly people. Design.—
Randomized double-blind placebo-controlled trial. Setting.—Fifteen family practices in the …

Background: Concern about the possibility that annually repeated influenza
immunizationmayinduce a lower antibody response than first vaccination. Objective: To …

Conflicting results have been reported concerning the association between high age and
response to influenza vaccines. Some authors have found a reduced response in aged …

The effects of yearly influenza immunization on the level of antibody responses were
assessed in 92 healthy elderly subjects immunized over four contiguous years (1993–1996) …

The objective of this study was to determine the immune response to influenza vaccination
in elderly people, using a randomized, double-blind, placebo-controlled trial. Venous blood …

Annual immunization against influenza is recommended for numerous individuals, but the
antibody response to sequential vaccination has not been well characterized. Levels of …

Doubt about the serologic efficacy of annually repeated influenza vaccination prompted
investigations into the course of hemagglutination-inhibiting (HI), IgG, and IgA antibody titers …

Objective: Each year, influenza and its complications account for 10,000-40,000 excess
deaths in the United States. Over 80% of these deaths occur among the elderly. The …

Some reports have suggested that influenza virus vaccine is less effective in persons that
have received prior annual vaccination (s) than in those receiving it for the first time. This …