A new MF59-adjuvanted influenza vaccine enhances the immune response in the elderly with chronic diseases: results from an immunogenicity meta-analysis

A Banzhoff, P Nacci, A Podda - Gerontology, 2003 - karger.com
Background: The elderly are at a higher risk of morbidity and mortality associated with
influenza infection than younger adults, but get less protection from conventional …

[HTML][HTML] Effectiveness of MF59-adjuvanted seasonal influenza vaccine in the elderly: a systematic review and meta-analysis

A Domnich, L Arata, D Amicizia, J Puig-Barberà… - Vaccine, 2017 - Elsevier
Background In the elderly, traditional influenza inactivated vaccines are often only modestly
immunogenic, owing to immunosenescence. Given that adjuvantation is a means of …

Comparison of the safety and immunogenicity of an MF59®-adjuvanted with a non-adjuvanted seasonal influenza vaccine in elderly subjects

SE Frey, MR Aplasca-De Los Reyes, H Reynales… - Vaccine, 2014 - Elsevier
Aim Adjuvanted influenza vaccines can overcome the poor antibody response of
conventional non-adjuvanted vaccines in the elderly. We evaluated the immunogenicity …

Comparative immunogenicity of enhanced seasonal influenza vaccines in older adults: a systematic review and meta-analysis

TWY Ng, BJ Cowling, HZ Gao… - The Journal of …, 2019 - academic.oup.com
Background A number of enhanced influenza vaccines have been developed for use in
older adults, including high-dose, MF59-adjuvanted, and intradermal vaccines. Methods We …

Long‐term and cross‐reactive immunogenicity of inactivated trivalent influenza vaccine in the elderly: MF59‐adjuvanted vaccine versus unadjuvanted vaccine

JY Song, HJ Cheong, JY Noh, YB Seo… - Journal of medical …, 2013 - Wiley Online Library
Elderly people are at great risk for influenza‐related serious complications. However,
influenza vaccine‐induced antibodies are believed to decline more rapidly in the elderly …

Safety and immunogenicity of MF59-adjuvanted influenza vaccine in the elderly

S De Donato, D Granoff, M Minutello, G Lecchi… - Vaccine, 1999 - Elsevier
Safety and immunogenicity of the influenza vaccine adjuvanted with MF59 (FLUADTM) were
compared to those of a non adjuvanted subunit vaccine in elderly subjects during three …

Comparison of the immunogenicity and safety of the conventional subunit, MF59-adjuvanted, and intradermal influenza vaccines in the elderly

YB Seo, WS Choi, J Lee, JY Song… - Clinical and vaccine …, 2014 - Am Soc Microbiol
The influenza vaccination is known as the most effective method for preventing influenza
infection and its complications in the elderly. Conventional subunit (Agrippal S1; Novartis) …

[HTML][HTML] Comparative effectiveness of adjuvanted versus high-dose seasonal influenza vaccines for older adults: a systematic review and meta-analysis

A Domnich, C de Waure - International Journal of Infectious Diseases, 2022 - Elsevier
Objectives MF59-adjuvanted standard-dose and nonadjuvanted high-dose seasonal
influenza vaccines have been developed to protect the elderly at high risk of severe …

Superior immunogenicity of seasonal influenza vaccines containing full dose of MF59® adjuvant: Results from a dose-finding clinical trial in older adults

G Della Cioppa, U Nicolay, K Lindert… - Human vaccines & …, 2012 - Taylor & Francis
Background: MF59-adjuvanted influenza vaccines have superior immunogenicity in older
adults compared with non-adjuvanted vaccines. We assessed whether changing formulation …

Comparison of the safety, tolerability, and immunogenicity of a MF59-adjuvanted influenza vaccine and a non-adjuvanted influenza vaccine in non-elderly adults

S Frey, G Poland, S Percell, A Podda - Vaccine, 2003 - Elsevier
The adjuvanted influenza vaccine FLUAD™ is composed of subunit influenza antigens
combined with the MF59-adjuvant emulsion. The vaccine was developed primarily for use in …