The reactogenicities and immunogenicities of two influenza virus vaccines were compared
in a placebo-controlled clinical trial among healthy ambulatory persons> or= 65 years old …

Background Influenza-related morbidity and mortality have been extensively studied with
hospital and reimbursement data. However, little is known about the effectiveness of the …

The objective of this study was to determine the immune response to influenza vaccination
in elderly people, using a randomized, double-blind, placebo-controlled trial. Venous blood …

Background Influenza-associated morbidity and mortality has not decreased in the last
decade, despite increased receipt of vaccine. To improve the immunogenicity of influenza …

Objective: To quantify the protective efficacy of influenza vaccine in elderly persons. Data
Sources: A MEDLINE search was done using the index terms influenza vaccine, vaccine …

Elderly individuals not only demonstrate a greater risk of morbidity and mortality from
influenza than the young, but also have greater difficulty mounting a protective response to …

Objective: Each year, influenza and its complications account for 10,000-40,000 excess
deaths in the United States. Over 80% of these deaths occur among the elderly. The …

Background Despite recommendations for annual vaccination against influenza, more than
half of elderly Americans do not receive this vaccine. In a serial cohort study, we assessed …

We performed a quantitative review of 31 vaccine antibody response studies conducted from
1986 to 2002 and compared antibody responses to influenza vaccine in groups of elderly …

▪ Objective: To evaluate the efficacy of adding intranasal live attenuated cold-adapted
influenza A vaccine to inactivated influenza vaccine to prevent influenza A in elderly …