Background Identifying optimal priming strategies for children< 2 years could substantially
improve the public health benefits of influenza vaccines. Adjuvanted seasonal influenza …

Background Young children have immature immune systems and respond poorly to
standard influenza vaccines. The oil-in-water emulsion adjuvant MF59 can increase antigen …

Background: Children have high morbidity and hospitalization rates from seasonal
influenza. Meta-analyses suggest that conventional inactivated influenza vaccines are of low …

Background: Vaccination against seasonal influenza is recommended for all children with a
history of medical conditions placing them at increased risk of influenza-associated …

Routine annual influenza immunization is increasingly recommended in young children. We
compared the safety and immunogenicity of vaccination with trivalent inactivated influenza …

Objective To assess the safety and immunogenicity of the MF59-adjuvanted seasonal
trivalent inactivated influenza vaccine (aIIV3; Fluad) in children aged 6 months through 5 …

Objective To demonstrate the potential of an MF59-adjuvanted inactivated trivalent seasonal
influenza vaccine (aIIV3; Fluad™) to improve the immune response in young children, we …

Young children are at increased risk for influenza infections and related complications. The
protection offered to children by conventional trivalent inactivated influenza vaccines (TIV) is …

Objectives This study was designed to identify the optimal dose of an MF59®-adjuvanted,
monovalent, A/H1N1 influenza vaccine in healthy paediatric subjects. Methods Subjects …

The poor immune response elicited by trivalent influenza vaccines (TIVs) in children can be
enhanced by the addition of adjuvants. This observer-blind, randomized Phase III trial …