Lipid-based Nanocarriers for mRNA Delivery: Vital Considerations and Applications
The use of mRNA in therapeutics has lately emerged as a powerful strategy for alleviating
the various viral infections and diseased conditions, along with prophylaxis. However, a key …
the various viral infections and diseased conditions, along with prophylaxis. However, a key …
Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach
Abstract mRNA vaccines have long been recognized for their ability to induce robust
immune responses. The discovery that mRNA vaccines may also contribute to antitumor …
immune responses. The discovery that mRNA vaccines may also contribute to antitumor …
Non-immunotherapy application of LNP-mRNA: Maximizing efficacy and safety
I Vlatkovic - Biomedicines, 2021 - mdpi.com
Lipid nanoparticle (LNP) formulated messenger RNA-based (LNP-mRNA) vaccines came
into the spotlight as the first vaccines against SARS-CoV-2 virus to be applied worldwide …
into the spotlight as the first vaccines against SARS-CoV-2 virus to be applied worldwide …
Brief Insights into mRNA Vaccines: Their Successful Production and Nanoformulation for Effective Response against COVID-19 and Their Potential Success for …
A Parveen, AA Elkordy - Pathogens, 2024 - mdpi.com
A mRNA vaccine is a type of vaccine that induces an immune response. Antigen-encoding
mRNA is delivered via vaccine carriers into the immune cells, which are produced because …
mRNA is delivered via vaccine carriers into the immune cells, which are produced because …
Nanomaterial delivery systems for mRNA vaccines
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …
development of lipid nanoparticle delivery systems that not only efficiently express the …
Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids
Messenger RNA (mRNA) can be harnessed as vaccines and therapeutic drugs via transient
in situ expression of protein antigens and therapeutic proteins, respectively. Currently …
in situ expression of protein antigens and therapeutic proteins, respectively. Currently …
The potential of mRNA vaccines in cancer nanomedicine and immunotherapy
S Pan, R Fan, B Han, A Tong, G Guo - Trends in Immunology, 2024 - cell.com
Owing to their outstanding performance against COVID-19, mRNA vaccines have brought
great hope for combating various incurable diseases, including cancer. Differences in the …
great hope for combating various incurable diseases, including cancer. Differences in the …
mRNA vaccine delivery using lipid nanoparticles
mRNA vaccines elicit a potent immune response including antibodies and cytotoxic T cells.
mRNA vaccines are currently evaluated in clinical trials for cancer immunotherapy …
mRNA vaccines are currently evaluated in clinical trials for cancer immunotherapy …
RNA cancer vaccines: developing mRNA nanovaccine with self-adjuvant property for cancer immunotherapy
H Zhang, X Xia - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
Messenger RNA (mRNA)-based cancer vaccine has become a popular approach for
developing personalized and effective antitumor immunotherapy. To achieve robust …
developing personalized and effective antitumor immunotherapy. To achieve robust …
Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects
In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid
nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of …
nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of …