Amorphous solid dispersions are a promising option for managing compounds with poor
aqueous solubility. However, for compounds with high melting points, thermal stability …

The toolbox of methods for generating amorphous solid dispersions, which are often critical
to achieving high kinetic solubility and bioavailability of drug molecules, continues to grow …

Amorphous solid dispersions (ASDs) are an attractive option to improve the bioavailability of
poorly water-soluble compounds. However, the material attributes of ASDs can present …

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral
absorption leading to poor bioavailability. Several approaches exist that improve the oral …

Amorphous solid dispersions (ASD) are a commonly used enabling formulation technology
to drive oral absorption of poorly soluble drugs. To ensure adequate solid-state stability and …

The understanding of amorphous solid dispersions has grown significantly in the past
decade. This is evident from the number of approved commercial amorphous solid …

Amorphous solid dispersions (ASD) have become a well-established strategy to improve
exposure for compounds with insufficient aqueous solubility. Of methods to generate ASDs …

Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

Amorphous solid dispersions (ASDs) are an enabling formulation approach used to
enhance bioavailability of poorly water-soluble molecules in oral drug products. Drug-rich …

Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …