Inflammatory responses are essential in eliminating harmful substrates from damaged tissue
and inducing recovery. Several cytokines participate in and facilitate this response. Certain …

Inflammasomes are an essential part of the innate immune system. They are necessary for
the development of a healthy immune response against infectious diseases. Inflammasome …

Introduction: The inflammasomes have emerged as key mediators of inflammation and
immunity, yet clinical application of this knowledge has been limited by a lack of specific and …

Through their capacity to sense danger signals and to generate active interleukin-1β (IL-1β),
inflammasomes occupy a central role in the inflammatory response. In contrast to IL-1β, little …

Inflammasomes are immune cytosolic oligomers involved in the initiation and progression of
multiple pathologies and diseases. The tight regulation of these immune sensors is …

Introduction The innate immune system orchestrates inflammatory responses to
microorganisms or danger-associated molecular patterns generated, for example, by the …

Induction, production, and release of proinflammatory cytokines are essential steps to
establish an effective host defense. Cytokines of the interleukin-1 (IL-1) family induce …

Maintenance of immune homeostasis is an intricate process wherein inflammasomes play a
pivotal role by contributing to innate and adaptive immune responses. Inflammasomes are …

Inflammasomes are assembled by innate immune sensors that cells employ to detect a
range of danger signals and respond with pro‐inflammatory signalling. Inflammasomes …

The inflammasomes are innate immune system receptors and sensors that regulate the
activation of caspase-1 and induce inflammation in response to infectious microbes and …