Amorphous solid dispersions (ASDs) are a promising formulation approach to improve the
solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. ASDs have …

Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …

Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

The use of amorphous solid dispersions is an interesting strategy to increase the
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …

Despite the fact that an amorphous solid dispersion (ASD)-coated pellet formulation offers
potential advantages regarding the minimization of physical stability issues, there is still a …

This work evaluates several compositions of an amorphous solid dispersion (ASD)
comprising nimodipine (NMD) as poorly soluble model API in a dual-polymer carrier system …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

Pharmaceutical excipients play a significant role in stabilization of amorphous solid
dispersions, as these systems are thermodynamically unstable. This chapter illustrates the …

Amorphous solid dispersion (ASD) is a formulation strategy extensively used to enhance the
bioavailability of poorly water soluble drugs. Despite this, they are limited by various factors …