Biopolymers have rarely been used so far as carriers in the formulation of amorphous solid
dispersions (ASD) to overcome poor solubility of active pharmaceutical ingredients (APIs). In …

Amorphous solid dispersions (ASDs) are a formulation and development strategy that can
be used to increase the apparent aqueous solubility of poorly water-soluble drugs. Their …

Understanding the long-term stability of amorphous solid dispersions (ASDs) is important for
their successful approval for market. ASD stability does not only depend on the interplay …

Presently, a large number of drug molecules in development are BCS class II or IV
compounds with poor aqueous solubility. Various novel solubilization techniques have been …

Polymeric amorphous solid dispersion (ASD) is a popular approach for enhancing the
solubility of poorly water-soluble drugs. However, achieving both physical stability and …

Miniaturised solvent casting (MSC) has been developed as a method for screening the
stability of amorphous solid dispersions (ASD) of BCS class II drugs. The aim of the work …

Oral delivery of poorly water-soluble, weakly basic drugs may be problematic based on the
drugs' intrinsic properties. Many drugs in this subset have overcome barriers to delivery …

Amorphous solid dispersions (ASD) have gained tremendous attention over the past two
decades as one of the most promising techniques for enhancing the solubility of poorly …

Amorphous systems have been applied effectively in the pharmaceutical industry for a
number of commercial and developmental products, although they are still considered a …

To reduce the pill burden associated with amorphous solid dispersions (ASDs), which arises
from the large quantity of polymer used in the formulation, it is of interest to understand the …