[HTML][HTML] The human antibody response to the influenza virus neuraminidase following infection or vaccination
M Rajendran, F Krammer, M McMahon - Vaccines, 2021 - mdpi.com
The influenza virus neuraminidase (NA) is primarily involved in the release of progeny
viruses from infected cells—a critical role for virus replication. Compared to the immuno …
viruses from infected cells—a critical role for virus replication. Compared to the immuno …
[HTML][HTML] Broadly protective neuraminidase-based influenza vaccines and monoclonal antibodies: Target epitopes and mechanisms of action
N Abbadi, JJ Mousa - Viruses, 2023 - mdpi.com
Neuraminidase (NA) is an important surface protein on influenza virions, playing an
essential role in the viral life cycle and being a key target of the immune system. Despite the …
essential role in the viral life cycle and being a key target of the immune system. Despite the …
The potential of neuraminidase as an antigen for nasal vaccines to increase cross-protection against influenza viruses
A Kawai, Y Yamamoto, T Nogimori, K Takeshita… - Journal of …, 2021 - Am Soc Microbiol
Despite the availability of vaccines that efficiently reduce the severity of clinical symptoms,
influenza viruses still cause substantial morbidity and mortality worldwide. In this regard …
influenza viruses still cause substantial morbidity and mortality worldwide. In this regard …
Contribution of antibody production against neuraminidase to the protection afforded by influenza vaccines
G Marcelin, MR Sandbulte… - Reviews in medical …, 2012 - Wiley Online Library
Vaccines are instrumental in controlling the burden of influenza virus infection in humans
and animals. Antibodies raised against both major viral surface glycoproteins …
and animals. Antibodies raised against both major viral surface glycoproteins …
[HTML][HTML] In the shadow of hemagglutinin: a growing interest in influenza viral neuraminidase and its role as a vaccine antigen
TJ Wohlbold, F Krammer - Viruses, 2014 - mdpi.com
Despite the availability of vaccine prophylaxis and antiviral therapeutics, the influenza virus
continues to have a significant, annual impact on the morbidity and mortality of human …
continues to have a significant, annual impact on the morbidity and mortality of human …
[HTML][HTML] Influenza neuraminidase: a neglected protein and its potential for a better influenza vaccine
LT Giurgea, DM Morens, JK Taubenberger, MJ Memoli - Vaccines, 2020 - mdpi.com
Neuraminidase (NA) is an influenza surface protein that helps to free viruses from mucin-
associated decoy receptors and to facilitate budding from infected cells. Experiments have …
associated decoy receptors and to facilitate budding from infected cells. Experiments have …
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
There is growing appreciation for neuraminidase (NA) as an influenza vaccine target;
however, its antigenicity remains poorly characterized. In this study, we isolated three …
however, its antigenicity remains poorly characterized. In this study, we isolated three …
[HTML][HTML] Influenza virus neuraminidase (NA): a target for antivirals and vaccines
Influenza, the most common infectious disease, poses a great threat to human health
because of its highly contagious nature and fast transmissibility, often leading to high …
because of its highly contagious nature and fast transmissibility, often leading to high …
Neuraminidase as an influenza vaccine antigen: a low hanging fruit, ready for picking to improve vaccine effectiveness
MC Eichelberger, DM Morens… - Current opinion in …, 2018 - Elsevier
Highlights•Neuraminidase (NA)-inhibiting antibodies are an independent correlate of
vaccine efficacy.•Many NA-specific antibodies bind to conserved epitopes and protect …
vaccine efficacy.•Many NA-specific antibodies bind to conserved epitopes and protect …
Influenza neuraminidase as a vaccine antigen
MC Eichelberger, H Wan - Influenza Pathogenesis and Control-Volume II, 2014 - Springer
Neuraminidase (NA) is the second most abundant influenza surface glycoprotein and
contributes to virus replication in several ways, most notably by removing sialic acids from …
contributes to virus replication in several ways, most notably by removing sialic acids from …
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