Standard-dose versus MF59-adjuvanted, high-dose or recombinant-hemagglutinin influenza vaccine immunogenicity in older adults: comparison of A (H3N2) …

S Zhong, TWY Ng, DM Skowronski… - The Journal of …, 2023 - europepmc.org
Background Annual influenza vaccination is recommended for older adults but repeated
vaccination with standard-dose influenza vaccine has been linked to reduced …

Immunogenicity and safety of a quadrivalent high-dose inactivated influenza vaccine compared with a standard-dose quadrivalent influenza vaccine in healthy people …

S Pepin, JF Nicolas, H Szymanski… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT A quadrivalent high-dose inactivated influenza vaccine (IIV4-HD) is licensed for
adults≥ 65 y of age based on immunogenicity and efficacy studies. However, IIV4-HD has …

Safety and immunogenicity of a trivalent single dose seasonal influenza vaccine containing pandemic A (H1N1) antigen in younger and elderly subjects: a phase III …

M Loebermann, G Anders, G Brestrich, C Fritzsche… - Vaccine, 2011 - Elsevier
BACKGROUND: During the pandemic of the 2009 A (H1N1) influenza virus strain, 20–40%
of the population in some areas were infected. Infection with A (H1N1) may be mild, with an …

[HTML][HTML] Immunogenicity and safety of Fluzone® intradermal and high-dose influenza vaccines in older adults≥ 65 years of age: A randomized, controlled, phase II …

P Tsang, GJ Gorse, CB Strout, M Sperling… - Vaccine, 2014 - Elsevier
We conducted a randomized, controlled, multicenter, phase II study to evaluate the
immunogenicity and safety of an investigational intradermal (ID) trivalent influenza vaccine …

Safety, immunogenicity, and tolerability of three influenza vaccines in older adults: results of a randomized, controlled comparison

DW Scheifele, SA McNeil, BJ Ward… - Human vaccines & …, 2013 - Taylor & Francis
To determine if newer influenza vaccines can safely improve seroprotection rates of older
adults, we compared three licensed trivalent inactivated vaccines (TIVs) in a randomized …

Long‐term and cross‐reactive immunogenicity of inactivated trivalent influenza vaccine in the elderly: MF59‐adjuvanted vaccine versus unadjuvanted vaccine

JY Song, HJ Cheong, JY Noh, YB Seo… - Journal of medical …, 2013 - Wiley Online Library
Elderly people are at great risk for influenza‐related serious complications. However,
influenza vaccine‐induced antibodies are believed to decline more rapidly in the elderly …

Comparative study of immunogenicity of split, intradermal and MF59-adjuvanted influenza vaccines in elderly institutionalized subjects

M Basileo, AM Iorio, G Bartolini, C Bianchini… - Procedia in …, 2014 - Elsevier
The reduced immunogenicity and effectiveness of influenza vaccines in subjects presenting
high risk of influenza-related complications, hospitalization and death, led the innovative …

Efficacy of high-dose versus standard-dose influenza vaccine in older adults

CA DiazGranados, AJ Dunning… - … England Journal of …, 2014 - Mass Medical Soc
Background As compared with a standard-dose vaccine, a high-dose, trivalent, inactivated
influenza vaccine (IIV3-HD) improves antibody responses to influenza among adults 65 …

[HTML][HTML] Antibody responses to intradermal or intramuscular MF59-adjuvanted influenza vaccines as evaluated in elderly institutionalized volunteers during a season …

B Camilloni, M Basileo, A Di Martino, I Donatelli… - Immunity & …, 2014 - Springer
Background The age-related weakening of the immune system makes elderly subjects less
responsive to influenza vaccination. In the last years, two “enhanced vaccines” were …

Safety and immunogenicity of a quadrivalent influenza vaccine in adults aged 60 years or above: a phase III randomized controlled clinical study

R Fan, X Huang, X Nian, Z Ou, J Zhou… - Human Vaccines & …, 2022 - Taylor & Francis
To control seasonal influenza epidemics in elders, a quadrivalent, inactivated, split-virion
influenza vaccine (IIV4) comprising A and B lineages is produced for young individuals and …