Inflammasomes, multiprotein platforms of caspase-1 activation, are assembled in response
to a number of exogenous and endogenous danger signals, leading to the production of pro …

The innate immune system is a dynamic and complex network for recognizing and
responding to cellular insult or tissue damage after infection or injury. The primary effector …

Inflammasomes are cytoplasmic multiprotein complexes comprising a sensor protein,
inflammatory caspases, and in some but not all cases an adapter protein connecting the two …

The inflammasomes are innate immune system receptors and sensors that regulate the
activation of caspase-1 and induce inflammation in response to infectious microbes and …

Inflammasomes are cytosolic multiprotein platforms assembled in response to invading
pathogens and other danger signals. Typically inflammasome complexes contain a sensor …

Inflammasomes are large cytosolic multiprotein complexes assembled in response to
infection and cellular stress, and are crucial for the activation of inflammatory caspases and …

Inflammasomes are supramolecular signaling complexes that activate a subset of caspases
known as the inflammatory caspases, an example of which is caspase 1. Upon stimulation …

The inflammasome is a multi-protein platform that assembles upon the presence of cues
derived from infection or tissue damage, and triggers the inflammatory response …

Inflammasomes are multimeric protein complexes that regulate inflammatory responses and
pyroptotic cell death to exert host defense against microbes. Intracellular pattern-recognition …

Inflammasomes are multiprotein signalling platforms that control the inflammatory response
and coordinate antimicrobial host defences. They are assembled by pattern-recognition …